Giant magnetoimpedance-based microchannel system for quick and parallel genotyping of human papilloma virus type 16/18

Hao Yang; Lei Chen; Chong Lei; Ju Zhang; Ding Li; Zhi-Min Zhou; Chen-Chen Bao; Heng-Yao Hu; Xiang Chen; Feng Cui; Shuang-Xi Zhang; Yong Zhou; Da-Xiang Cui
July 2010
Applied Physics Letters;7/26/2010, Vol. 97 Issue 4, p043702
Academic Journal
Quick and parallel genotyping of human papilloma virus (HPV) type 16/18 is carried out by a specially designed giant magnetoimpedance (GMI) based microchannel system. Micropatterned soft magnetic ribbon exhibiting large GMI ratio serves as the biosensor element. HPV genotyping can be determined by the changes in GMI ratio in corresponding detection region after hybridization. The result shows that this system has great potential in future clinical diagnostics and can be easily extended to other biomedical applications based on molecular recognition.


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