Growth in Vascular Cells and Cytokine Production by Chlamydia pneumoniae

Gaydos, Charlotte A.
June 2000
Journal of Infectious Diseases;6/15/2000 Supplement 3, Vol. 181, pS473
Academic Journal
Proposes the need for studies to learn the relationship between productive infection and persistence, the ability of Chlamydia pneumoniae to affect the immune response, and the potential for C. pneumoniae to influence atheromatous lesions. Proposed pathogenesis of C. pneumoniae in atherosclerosis; Locations of in vitro growth of the organism; Transmission of the infection to human coronary artery endothelial cells.


Related Articles

  • Detection of Chlamydia pneumoniae within Peripheral Blood Monocytes of Patients with Unstable Angina or Myocardial Infarction. Maass, Matthias; Jahn, Jurgen; Gieffers, Jens; Dalhoff, Klaus; Katus, Hugo A.; Solbach, Werner // Journal of Infectious Diseases;6/15/2000 Supplement 3, Vol. 181, pS449 

    Presents a study that uses polymerase chain reaction detection of chlamydial DNA applied to cells from patients with angiographically identified unstable angina or acute myocardial infarction. Presence of Chlamydia pneumoniae in monocytes/macrophages of a significant proportion of persons with...

  • Chlamydia pneumoniae and Coronary Artery Disease: The Antibiotic Trials. Higgins, John P. // Mayo Clinic Proceedings;Mar2003, Vol. 78 Issue 3, p321 

    Discusses the potential role of Chlamydia pneumoniae infection in atherosclerosis. Randomized clinical trials of antichlamydial antibiotics in patients with coronary heart disease; Detection of infection; Four classes of antibiotics against infection; Specific factors that may link Chlamydia...

  • Chlamydia pneumoniae e doença aterosclerótica. Sehnem, Luciele; Bodanese, Luiz Carlos; Repetto, Giuseppe; Staub, Henrique Luiz // Scientia Medica;Sep2010, Vol. 20 Issue 3, p250 

    Aims: To study the etiopathogenic role of Chlamydia pneumoniae infection in the atherosclerotic disease, in vitro studies and animal models involving Chlamydia pneumonia and atheromatosis were reviewed, as well as clinical assays that analyzed the association between the pathogen and...

  • Association between past infection with Chlamydia pneumoniae and body mass index, low-density lipoprotein particle size and fasting insulin. Dart, A.M.; Martin, J.L.; Kay, S. // International Journal of Obesity & Related Metabolic Disorders;Apr2002, Vol. 26 Issue 4, p464 

    Investigates the association between Chlamydia pneumoniae infection history and coronary heart disease (CHD) risk factors. Body mass index; Prevalence of seropositivity for subjects with and without CHD; Fasting insulin level; Low-density-lipoprotein particles.

  • Antibiotic Trials for Coronary Heart Disease. Anderson, Jeffrey L.; Muhlestein, Joseph B.; Casscells, S. Ward; Madjid, Mohammad // Texas Heart Institute Journal;2004, Vol. 31 Issue 1, p33 

    The possibility has been raised in recent years that infection might contribute as an inflammatory stimulus to chronic "noninfectious" degenerative diseases. Within the past decade, serious attention has been given to the possibility of bacterial vectors as causal factors of atherosclerosis. To...

  • Chlamydia pneumoniae Infection Accelerates the Progression of Atherosclerosis in Apoliopoprotein E-Deficient Mice. Moazed, Teresa C.; Campbell, Lee Ann; Rosenfeld, Michael E.; Grayston, J. Thomas; Cho-chou Kuo // Journal of Infectious Diseases;7/1/99, Vol. 180 Issue 1, p238 

    Analyzes whether there is a causal relationship between Chlamydia pneumoniae infection and atherosclerosis. Effects of chronic infection with C. pneumoniae on the development of atherosclerosis; Differences in total plasma cholesterol levels between the study and control groups; Progression of...

  • Collaborative Multidisciplinary Workshop Report: Progress toward a Chlamydia pneumoniae Vaccine. Murdin, Andrew D.; Gellin, Bruce; Brunham, Robert C.; Campbell, Lee Ann; Christiansen, Gunna; Deal, Carolyn D.; Jenson, Hal B.; Metcalf, Benjamin; Sankaran, Banu; Stephens, Richard S.; Wilfert, Cathy // Journal of Infectious Diseases;6/15/2000 Supplement 3, Vol. 181, pS552 

    Discusses a multidisciplinary workshop report on the progress toward a Chlamydia pneumoniae vaccine. Association of C. pneumoniae with atherosclerosis; Information necessary to develop a safe vaccine and to initiate trials; Ways by which the disciplines represented by other meeting workshop...

  • Chlamydia pneumoniae in Atherosclerotic Tissue. Taylor-Robinson, D.; Thomas, B. J. // Journal of Infectious Diseases;6/15/2000 Supplement 3, Vol. 181, pS437 

    Discusses the presence of Chlamydia pneumoniae organisms within foam and smooth muscle cells of atherosclerotic plaques and their role in atherosclerosis. Association between C. pneumoniae and coronary artery disease based on serologic studies; Evidence of C. pneumoniae in atherosclerotic...

  • Chlamydia pneumoniae Infection and Incident Coronary Heart Disease. Nieto, F. Javier; Folsom, Aaron R.; Sorlie, Paul D.; Grayston, J.Thomas; Wang, San-Pin; Chambless, Lloyd E. // American Journal of Epidemiology;1999, Vol. 150 Issue 2, p149 

    Pathologic findings and cross-sectional epidemiologic studies suggest that past infection with Chlamydia pneumoniae is associated with clinical and subclinical atherosclerotic disease, although evidence from prospective studies is still scarce. The association between chronic infection by C....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics