Rationalizing the clinical use of frozen plasma

Pinkerton, Peter H.; Callum, Jeannie L.
July 2010
CMAJ: Canadian Medical Association Journal;7/13/2010, Vol. 182 Issue 10, p1019
Academic Journal
The article offers the authors' views on the clinical use of frozen plasma. The authors note that most of the use of frozen plasma lacks objective evidence to support its value and it contributes to the mortality and morbidity resulting from transfusion of blood components. They cite the studies in Canada showing that 45.0% and 47.6% of frozen plasma transfusions represented improper use. They also mention that more clinical trials are needed to determine the correct usage of frozen plasma.


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