A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Armodafinil for Excessive Sleepiness Associated With Jet Lag Disorder
- Non-pharmacological treatments for insomnia. Ebben, Matthew R.; Spielman, Arthur J. // Journal of Behavioral Medicine;Jun2009, Vol. 32 Issue 3, p244
Insomnia is a common disorder effecting millions of people worldwide. Currently most individuals suffering from insomnia take medications to help them sleep. However, there are a variety of behavioral treatments, which have been shown to be effective in empirical studies that offer many...
- Transdermal Absorption of ( )-Linalool Induces Autonomic Deactivation but has No Impact on Ratings of Well-Being in Humans. Heuberger, Eva; Redhammer, Sandra; Buchbauer, Gerhard // Neuropsychopharmacology;Oct2004, Vol. 29 Issue 10, p1925
Essential lavender oil has a long tradition as a mild sedative in herbal medicine. Relaxing effects after inhalation have also been demonstrated for one of its main constituents, (-)Linalool. The aim of the present investigation was to determine the effects of this monoterpenoid alcohol on human...
- Desperately Seeking Shut-eye. Lang, Jennifer // Natural Solutions;Jul/Aug2008, Issue 109, p60
The article provides an age-by-age guide on how to manage insomnia in the U.S. The author stated that the physiological reason for young adults to have sleep disorder is that their circadian rhythm is in flux, thus taking a bath or shower before getting into bed is suggested. Meanwhile, the...
- ï¿½-CIT SPECT demonstrates reduced availability of serotonin transporters in patients with Fatal Familial Insomnia. Kl�ppel, S.; Pirker, W.; Br�cke, T.; Kov�cs, G. G.; Almer, G. // Journal of Neural Transmission;Jul2002, Vol. 109 Issue 7/8, p1105
Summary. Fatal familial insomnia (FFI) is a rare hereditary human prion disease with unique clinical features including progressive sleep impairment and autonomic dysfunction. The serotonergic system is considered to be involved in the regulation of the sleep-wake cycle. In this study we...
- A Missense Variation in Human Casein Kinase 1 Epsilon Gene that Induces Functional Alteration and Shows an Inverse Association with Circadian Rhythm Sleep Disorders. Takano, Atsuko; Uchiyama, Makoto; Kajimura, Naofumi; Mishima, Kazuo; Inoue, Yuichi; Kamei, Yuichi; Kitajima, Tsuyoshu; Shibui, Kayo; Katoh, Masaaki; Watanabe, Tsuyoshu; Hashimotodan, Yuki; Nakajima, Toru; Ozeki, Yuji; Hori, Toru; Yamada, Naoto; Toyoshima, Ryoichi; Ozaki, Norio; Okawa, Masako; Nagai, Katsuya; Takahashi, Kiyohisa // Neuropsychopharmacology;Oct2004, Vol. 29 Issue 10, p1901
Recent studies have shown that functional variations in clock genes, which generate circadian rhythms through interactive positive! negative feedback loops, contribute to the development of circadian rhythm sleep disorders in humans. Another potential candidate for rhythm disorder susceptibility...
- SNOOZE CONTROL. // New Scientist;2/23/2002, Vol. 173 Issue 2331, p38
Analyzes the pattern of sleep-wake disturbances. Way of diagnosing and treating sleeping disorders; Intervals between signals in human neurons; Explanation of the phenomenon of sleep walking.
- sleep-wake cycle. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2143
A definition of the term "sleep-wake cycle," which refers to the amount of time spent asleep and awake and the cycle of that schedule from day to day, is presented.
- Beating the Clock. // Professional Safety;Jan2014, Vol. 59 Issue 1, p48
The article discusses waking up before one's alarm clock and the science behind human circadian rhythms, including the protein PER.
- Circadian rhythm is the 'internal clock' that makes you sleepy at night. // Mayo Clinic Health Letter;Oct2001 Suplement, Vol. 19 Issue 10, p5
Focuses on a person's circadian rhythm, the natural pattern of waking and sleeping that occurs within a 24-hour day. Influence on physical functions that usually induces sleep at night and wakes a person up in the morning; Changes in a people's circadian rhythm as they age; Factors that can...