Sexual Abuse and Lifetime Diagnosis of Psychiatric Disorders: Systematic Review and Meta-analysis

Chen, Laura P.; Murad, M. Hassan; Paras, Molly L.; Colbenson, Kristina M.; Sattler, Amelia L.; Goranson, Erin N.; Elamin, Mohamed B.; Seime, Richard J.; Shinozaki, Gen; Prokop, Larry J.; Zirakzadeh, Ali
July 2010
Mayo Clinic Proceedings;Jul2010, Vol. 85 Issue 7, p618
Academic Journal
OBJECTIVE: To systematically assess the evidence for an association between sexual abuse and a lifetime diagnosis of psychiatric disorders. PATIENTS AND METHODS: We performed a comprehensive search (from January 1980-December 2008, all age groups, any language, any population) of 9 databases: MEDLINE, EMBASE, CINAHL, Current Contents, PsycINFO, ACP Journal Club, CCTR, CDSR, and DARE. Controlled vocabulary supplemented with keywords was used to define the concept areas of sexual abuse and psychiatric disorders and was limited to epidemiological studies. Six independent reviewers extracted descriptive, quality, and outcome data from eligible longitudinal studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were pooled across studies by using the random-effects model. The I2 statistic was used to assess heterogeneity. RESULTS: The search yielded 37 eligible studies, 17 case-control and 20 cohort, with 3,162,318 participants. There was a statistically significant association between sexual abuse and a lifetime diagnosis of anxiety disorder (OR, 3.09; 95% CI, 2.43-3.94), depression (OR, 2.66; 95% CI, 2.14-3.30), eating disorders (OR, 2.72; 95% CI, 2.04-3.63), posttraumatic stress disorder (OR, 2.34; 95% CI, 1.59-3.43), sleep disorders (OR, 16.17; 95% CI, 2.06-126.76), and suicide attempts (OR, 4.14; 95% CI, 2.98-5.76). Associations persisted regardless of the victim's sex or the age at which abuse occurred. There was no statistically significant association between sexual abuse and a diagnosis of schizophrenia or somatoform disorders. No longitudinal studies that assessed bipolar disorder or obsessive-compulsive disorder were found. Associations between sexual abuse and depression, eating disorders, and posttraumatic stress disorder were strengthened by a history of rape. CONCLUSION: A history of sexual abuse is associated with an increased risk of a lifetime diagnosis of multiple psychiatric disorders.


Related Articles

  • Old drug ifenprodil, new hope for PTSD with a history of childhood abuse. Hashimoto, Kenji; Sasaki, Tsuyoshi; Kishimoto, Akira // Psychopharmacology;May2013, Vol. 227 Issue 2, p375 

    No abstract available.

  • My Spirit Lives. Chinook, Roxanne // Social Justice;2004, Vol. 31 Issue 4, p31 

    The article presents the author's experiences as she recovered from post-traumatic stress disorder. I am a proud tribal member of the Confederated Tribes of the Warm Springs Indian Reservation, a professional artist, and a college graduate. I stand proud today because I am finally healing from...

  • A QUALITATIVE ANALYSIS OF STRENGTHS AND VULNERABILITIES IN SEXUALLY ASSAULTED WOMEN. Regehr, Cheryl; Marziali, Elsa; Jansen, Karen // Clinical Social Work Journal;Summer99, Vol. 27 Issue 2, p171 

    Clinicians and researchers alike have pointed to the considerable variation in trauma responses among women who have been raped. This qualitative study attempts to enhance the understanding of strengths and vulnerabilities in women who have been sexually assaulted and factors which influence...

  • Correlation of Sleep Disturbances, Anxiety and Depression in Croatian War Veterans with Posttraumatic Stress Disorder. Jevtović, Saša; Gregurek, Rudolf; Kalenić, Barbara; Brajković, Lovorka; Braš, Marijana; Lončar, Mladen; Germain, Anne // Collegium Antropologicum;Mar2011 Supplement 1, Vol. 35, p175 

    The aim of the study was to examine the relationships between global sleep quality and its specific components and Posttraumatic Stress Disorder (PTSD) symptom severity questionnaire. We also researched whether sleep quality and sleep disturbances differed among groups of PTSD based on symptom...

  • Conceptualizing Treatment Nonadherence in Patients with Bipolar Disorder and PTSD. Rakofsky, Jeffrey J.; Levy, Steven T.; Dunlop, Boadie W. // CNS Spectrums: The International Journal of Neuropsychiatric Med;Jan2011, p2 

    Treatment nonadherence is a concern among patients with bipolar disorder and posttraumatic stress disorder (PTSD). PTSD is common among patients with bipolar disorder and those with this comorbidity often have a more severe course of illness. While many factors have been associated with...

  • Applying the brakes. Rothschild, Babette // CPJ: Counselling & Psychotherapy Journal;Feb2005, Vol. 16 Issue 1, p12 

    The article presents an account of the experiences of people suffering from post-traumatic stress disorder. These people included a nurse, a businesswoman, a salesman, a therapist and other men and women who had functioned relatively well prior to trauma therapy. Yet after attempts to address...

  • Age at Sexual Assault And Posttraumatic Stress Disorder among Women: Prevalence, Correlates, And Implications for Prevention. Masho, Saba W.; Ahmed, Gasmelseed // Journal of Women's Health (15409996);Mar2007, Vol. 16 Issue 2, p262 

    Background: Posttraumatic stress disorder (PTSD) is a debilitating psychiatric condition that can occur in people who experience extremely stressful or traumatic life events. Sexual assault is one of the most traumatic stressors in life. Although several studies have investigated the association...

  • The Various Care Requirements of Psychotraumatized Subjects: From Linguistic Desert to Therapeutic Perspectives. Auxemery, Yann // Journal of Trauma & Treatment;2012, Vol. 1 Issue 6, Special section p1 

    Background: The cardinal symptoms of posttraumatic stress disorder, which is exhibited as intrusions, avoidance strategies and hypervigilance, are rarely highlighted by psycho traumatized patients when they seek care. Furthermore, the clinical features of posttraumatic stress disorder (PTSD)...

  • Determinants of the development of post-traumatic stress disorder, in the general population. Perrin, Marc; Vandeleur, Caroline; Castelao, Enrique; Rothen, Stéphane; Glaus, Jennifer; Vollenweider, Peter; Preisig, Martin // Social Psychiatry & Psychiatric Epidemiology;Mar2014, Vol. 49 Issue 3, p447 

    Purpose: To assess (1) the lifetime prevalence of exposure both to trauma and post-traumatic stress disorder (PTSD); (2) the risk of PTSD by type of trauma; and (3) the determinants of the development of PTSD in the community. Methods: The Diagnostic Interview for Genetic Studies was...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics