TITLE

Urine iodine concentration in neonates with congenital hypothyroidism

AUTHOR(S)
Al Jurayyan, Nasir A. M.; El Desouki, Mahmoud I.; Al Nuaim, Abdulrahman A.; Al At-tas, Omar S.; Al Dagheri, Nasser
PUB. DATE
January 2010
SOURCE
Current Pediatric Research;Jan2010, Vol. 14 Issue 1, p47
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
To examine the possible role of iodine in the aetiology of congenital hypothyroidism, urinary iodine concentration was compared in 23 neonates with congenital hypothyroidism detected by neonatal screening program in Riyadh region (mean cord TSH 403 ±123 mU/L), and their mothers. Twenty-five normal neonates (mean cord TSH 6.74 ± 4.03 mU/L) were randomly selected as control. The mean urine iodine concentration of the congenital hypothyroid group was 21.3 ± 11.2 μg/dl, which was significantly (P<0.05) higher than their mothers with mean of 16.3 ± 7.5 μg/dl, and the control group; mean 14.4 ± 4.6 μg/dl. We conclude that neonates with congenital hypothyroidism have normal iodine concentration, and that iodine does not seem to play a role in the aetiological diagnosis of congenital hypothyroidism.
ACCESSION #
51892691

 

Related Articles

  • The role of ultrasonography in primary congenital hypothyroidism. Hashemipour, Mahin; Rostampour, Noushin; Nasry, Peyman; Hovsepian, Silva; Basiratnia, Reza; Hekmatnia, Ali; Hossein Shahkarami, Amir; Mehrabi, Ali; Hadian, Rezvane; Amini, Massoud // Journal of Research in Medical Sciences;Sep2011, Vol. 16 Issue 9, p1122 

    BACKGROUND: The aim of this study was to compare the usefulness of ultrasonography and scintigraphy in diagnosing the etiology of primary congenital hypothyroidism (CH). METHODS: The newborns that were examined by both thyroid scintigraphy and ultrasonography during CH screening program in...

  • Goiter.  // Diseases & Disorders: A Nursing Therapeutics Manual, 3rd edition;2007, p378 

    The article provides clinical information on goiter, a disease characterized by the enlargement of the thyroid gland. The physiological mechanism underlying goiter is discussed. The causes, genetic and racial aspects of the disease are presented. The clinical diagnosis and therapeutic management...

  • Editor's note.  // Wellness Options;2007, Issue 34, p31 

    The article presents an overview of the importance of thyroid hormones in early brain development and maturation in fetuses. A discussion of the importance of thyroid screening in pregnant women and of the role iodine deficiency plays in the development of congenital hypothyroidism in newborns,...

  • Time to take iodine deficiency more seriously.  // Australian Nursing Journal;Jul2002, Vol. 10 Issue 1, p30 

    Focuses on a research which examined iodine deficiency in Australian neonates. Reference to the study; Methods and findings of the study; Suggestions from the research authors.

  • Time to take iodine deficiency more seriously.  // Australian Nursing Journal;Jul2002, Vol. 10 Issue 1, p30 

    Focuses on a research which examined iodine deficiency in Australian neonates. Reference to the study; Methods and findings of the study; Suggestions from the research authors.

  • Iodine deficiency: a probable cause of neural tube defect. Sarici, Dilek; Akin, Mustafa; Kurtoglu, Selim; Akin, Leyla; Tucer, Bulent; Yikilmaz, Ali; Gokoglu, Abdulkerim // Child's Nervous System;Jun2013, Vol. 29 Issue 6, p1027 

    Introduction: Iodine deficiency is the most devastating event in developing brain in the fetus and neonate. Iodine is absolutely necessary on the myelination, neuronal differentiation, and formation of neural processes, synaptogenesis, and neuronal migration by thyroidal hormones throughout...

  • A Review on the Metabolic Disorders of Iodine Deficiency. Mansourian, Azad Reza // Pakistan Journal of Biological Sciences;2011, Vol. 14 Issue 7, p412 

    Iodine is in the crucial parts of two hormones of T4 and T3 produced by the thyroid glands which are essential for all the aspects of human metabolisms. It is demonstrated that iodine deficiency can be considered as sole cause of many thyroid abnormalities including mental disorders. Iodine...

  • Avicenna, the First to Describe Thyroid-Related Orbitopathy. Iraj Nabipour; Albert Burger; Muhammad-Reza Moharreri; Fereidoun Azizi // Thyroid;Jan2009, Vol. 19 Issue 1, p7 

    The history of the association of goiter and orbital disease is discussed. Although Graves and Basedow are credited with the first descriptions of this association, it was described many years earlier between AD 1000 and 1110 by two Persian physicians and philosophers, Avicenna and Al-Jurjani.

  • Thyroid enlargement. Toft, Anthony D. // British Medical Journal (Clinical Research Edition);4/6/1985, Vol. 290 Issue 6474, p1066 

    Focuses on the characteristics of thyroid enlargement. Influence of iodine deficiency; Development of Graves disease; Diagnosis of medullary carcinoma.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics