TITLE

Possible role of oxidative stress in malnourished children

AUTHOR(S)
Perampalli, Tasneem; Swami, S. C.; Kumbar, K. M.; Suryakar, A. N.; Shaikh, Abdul Kayyum
PUB. DATE
January 2010
SOURCE
Current Pediatric Research;Jan2010, Vol. 14 Issue 1, p19
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The present study was undertaken to uncover the possible role of oxidative stress in PEM children. Based on signs and symptoms. Forty five malnourished children around the age group of 1-5 years were divided into 3 groups, - viz Marasmus, Marasmic- Kwashiorkor and Kwashiorkor. Thirty children from same age group were taken as control. Study revealed highly significant increased Levels of Malondialdehyde (MDA), Nitric oxide(NO•) and Erythrocytic glucose 6 phosphate dehydrogenase (RBC-G6PD) activity [p<0.001], where as the levels of vitamin E, Total serum protein, and serum Albumin were significantly de-creased in malnourished children as compared with healthy controls. From the present ob-servations, it is evident that, scarcity of principal nutrients, which are part of antioxidant defense were decreased, resulting in oxidative stress.
ACCESSION #
51892685

 

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