TITLE

Retroperitoneal Soft Tissue Sarcomas: Experience at a Single Institution in Mexico

AUTHOR(S)
García-Aceituno, Luis; Villarreal-Garza, Cynthia; Perfecto, Miguel; León-Rodríguez, Eucario
PUB. DATE
July 2010
SOURCE
World Journal of Surgery;Jul2010, Vol. 34 Issue 7, p1511
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Retroperitoneal soft tissue sarcomas (RSTS) are a rare and uncommon entity with a poor 5-year overall survival (OS) of approximately 50%, even though they rarely metastasize. The aim of the present study was to analyze the survival of patients with RSTS treated at our institution. Patients with RSTS treated between 1990 and 2008 were included. Variables analyzed were age, sex, histological type, TNM stage, tumor size, grade of differentiation, and treatment (surgery, chemotherapy only, radiotherapy only, adjuvant radiotherapy, and best supportive care). R0, R1, and R2 resection were analyzed. Overall survival, recurrence-free survival (RFS), cancer-specific survival (CSS), and survival comparison by stage, grade, and type of resection were analyzed. Data for 46 patients were analyzed, 20 men and 26 women. Median age was 51.1 years. Surgery with a curative intent was performed in 32 patients, and R0 resection was feasible in 19 (59.4%). The 5- and 10-year OS rates were 47 and 30%, respectively, for the entire group. The median CSS for resected patients was 102 months; the 5-year OS for stages I, III, and IV was 83, 37, and 0%, respectively; the 5-year OS for low histological grade disease and high histological grade disease was 82 and 35%, respectively; and for R0, R1, and R2 resection, the 5-year OS was 81, 56, and 14%, respectively. Median RFS was 79 months. Incomplete surgical resection, unresectable disease, high histological grade, and advanced TNM stage are associated with a poor survival in patients with RSTS. Complete resection is still the treatment of choice.
ACCESSION #
51880570

 

Related Articles

  • The Role of Pulmonary Resection in Small Cell Lung Cancer. Chandra, Vidhan; Allen, Mark S.; Nicholls III, Francis C.; Deschamps, Claude; Cassivi, Stephen D.; Pairolero, Peter C. // Mayo Clinic Proceedings;May2006, Vol. 81 Issue 5, p619 

    OBJECTIVE: To analyze the outcome of surgical resection for patients with small cell lung cancer (SCLC). PATIENTS AND METHODS: We identified all patients who underwent thoracotomy for SCLC at our institution from January 1985 to July 2002. All patients were staged using the American Joint...

  • Primary Ewing’s sarcoma of the maxilla: a patient report. Ülkür, E.; Açikel, C.; Aydin, T.; Çeliköz, B. // European Journal of Plastic Surgery;Jun2004, Vol. 27 Issue 3, p140 

    Primary Ewing’s sarcoma rarely arises in the facial skeleton and only occasionally in the maxilla. To date, there have been 22 cases of maxillary Ewing’s sarcoma reported in the English-language literature. We report a case arising in the maxilla, successfully treated by wide...

  • Short-term followup after surgical treatment of Ewing's sarcoma. Rastogi, Shishir; Kumar, Ashok; Gupta, Himanshu; Khan, Shah Alam; Bakhshi, Sameer // Indian Journal of Orthopaedics;Oct-Dec2010, Vol. 44 Issue 4, p384 

    Background: Results of surgical treatment in Indian patients of Ewing's sarcoma managed with multimodality treatment with chemotherapy and/or radiotherapy are insufficient. We report a retrospective evaluation of a series of cases of Ewing's sarcoma managed with chemotherapy, surgery with or...

  • A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer. Ueno, H.; Kosuge, T.; Matsuyama, Y.; Yamamoto, J.; Nakao, A.; Egawa, S.; Doi, R.; Monden, M.; Hatori, T.; Tanaka, M.; Shimada, M.; Kanemitsu, K. // British Journal of Cancer;9/8/2009, Vol. 101 Issue 6, p908 

    Background:This multicentre randomised phase III trial was designed to determine whether adjuvant chemotherapy with gemcitabine improves the outcomes of patients with resected pancreatic cancer.Methods:Eligibility criteria included macroscopically curative resection of invasive ductal carcinoma...

  • Asymptomatic isolated coccygeal metastasis in low rectal carcinoma. Stewart, Duncan; Kitsanta, P.; Hampton, J.; Shorthouse, A. // Techniques in Coloproctology;Sep2011, Vol. 15 Issue 3, p349 

    As well as being relatively rare, osseous metastases from colorectal cancer are frequently asymptomatic and represent a late manifestation of disease. We report a case of an unidentified, asymptomatic coccygeal metastasis discovered on histological processing of the resection specimen from a...

  • Increased CD133 expression after preoperative chemoradiotherapy in rectal cancers other than mucin-rich tumors. Lin, Chih-Hung; Chen, Wan-Tzu; Liu, Chia-Hsing; Tsai, Hung-Pei; Wu, Chun-Chieh; Chai, Chee-Yin // Virchows Archiv;May2012, Vol. 460 Issue 5, p447 

    This study is to characterize the sequential change in CD133 expression after preoperative chemoradiotherapy (CRT) in rectal cancer and its impact on postoperative prognosis. Forty-one patients with rectal cancer who had received CRT before surgery were selected retrospectively. In each case,...

  • Caught in the middle: case study of a brachial (sentry) lymph node recurrence after resection and locoregional breast radiotherapy. Lee, G.; Clemons, M.; Cho, J.; Czarnota, G. J.; Dinniwell, R. // Current Oncology;Jun2012, Vol. 19 Issue 3, pe211 

    To reduce local recurrence, adjuvant locoregional radiotherapy is given routinely for post-mastectomy breast patients with 4 or more positive lymph nodes. Most institutions adopt a 3- or 4-field radiotherapy technique, in which the field and shielding placements are informed by bony anatomic...

  • Distal clearance margin of 1 cm or less: a safe distance in lower rectum cancer surgery. Leo, Ermanno; Belli, Filiberto; Miceli, Rosalba; Mariani, Luigi; Gallino, GianFrancesco; Battaglia, Luigi; Vannelli, Alberto; Andreola, Salvatore // International Journal of Colorectal Disease;Mar2009, Vol. 24 Issue 3, p317 

    The purpose of this study was to investigate the prognostic role of distal clearance margin (DCM) in lower rectum cancer surgery. Two-hundred-three cancer patients underwent total rectal resection, possibly followed by adjuvant chemoradiotherapy. DCM was classified as positive or negative (<1,...

  • Cancer concerns. Gagnon, Louise // Cosmetic Surgery Times;Oct2012, Vol. 15 Issue 9, p4 

    The article offers information on a statement by the U.S. Food and Drug Administration (FDI) regarding association between breast implants and anaplastic large-cell lymphoma (ALCL). It informs that the most common presentation of ALCL in breast implant population is a unilateral late seroma but...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics