TITLE

Note: Three-omega method to measure thermal properties of subnanoliter liquid samples

AUTHOR(S)
Byoung Kyoo Park; Jaesung Park; Dongsik Kim
PUB. DATE
June 2010
SOURCE
Review of Scientific Instruments;Jun2010, Vol. 81 Issue 6, p066104
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
There are growing needs to measure the thermal properties of small-volume liquid samples in various fields of bioengineering and microfluidics. Accordingly, there have been efforts toward miniaturization of the sensing device without substantially sacrificing the sensitivity. The minimum sample volume required for quantitative thermal analysis is currently in the 10 nl scale. In this work, we describe microfabricated sensors and a modified three-omega data-analysis scheme to determine the thermal conductivity k and volumetric heat capacity ρcp of samples of a few hundred picoliters. In experiments using several reference liquids, the technique measured k and ρcp of 750 and 375 pl samples. The measurement accuracies were ∼10% for k and ∼15% for ρcp.
ACCESSION #
51848923

 

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