Avoidance and Management of Complications of Total Parenteral Nutrition

Khaodhiar, Lalita; Bistrian, Bruce R.
July 1999
Nutrition in Clinical Care;Jul/Aug99, Vol. 2 Issue 4, p239
Academic Journal
Abstract Total parenteral nutrition therapy can be life-saving for specific groups of patients, but is not without risks. Complications that may occur are divided into three groups: mechanical, infectious, and metabolic. While mechanical complications related to central venous catheter placement can be minimized by the skill and experience of the operator, infectious and metabolic complications, such as hyperglycemia and electrolyte abnormalities, are more likely to be decreased by careful observation and monitoring of the patient. Certain guidelines, which are presented here, should be followed to prevent such complications, while problems that may occur should be recognized and treated promptly.


Related Articles

  • Spreading cortical venous thrombosis due to infusion of hyperosmolar solution into the internal jugular vein. Souter, R.G.; Mitchell, A. // British Medical Journal (Clinical Research Edition);10/2/1982, Vol. 285 Issue 6346, p935 

    Examines the occurrence of cortical venous thrombosis due to infusion of hyperosmolar parenteral nutrition fluid. Catheterization of the percutaneous subclavian vein for the total parenteral nutrition (TPN); Effect of the misplaced venous catheter; Findings on the development thrombosis due to...

  • Hyperglycemia During Total Parenteral Nutrition. Pasquel, Francisco J.; Spiegelman, Ronnie; McCauley, Megan; Smiley, Dawn; Umpierrez, Denise; Johnson, Rachel; Rhee, Mary; Gatcliffe, Chelsea; Lin, Erica; Umpierrez, Erica; Peng, Limin; Umpierrez, Guillermo E. // Diabetes Care;Apr2010, Vol. 33 Issue 4, p739 

    OBJECTIVE -- To determine the effect of total parenteral nutrition (TPN)-induced hyperglycemia on hospital outcome. RESEARCH DESIGN AND METHODS -- The study determined whether blood glucose values before, within 24 h, and during days 2-10 of TPN are predictive of hospital complications and...

  • Total Parenteral Nutrition Is a Major Risk Factor for Central Venous Catheter-Related Bloodstream Infection in Colorectal Cancer Patients Receiving Postoperative Chemotherapy. Ishizuka, M.; Nagata, H.; Takagi, K.; Kubota, K. // European Surgical Research;2008, Vol. 41 Issue 4, p341 

    Purpose: To clarify the risk factors for central venous catheter-related bloodstream infection (CVCR-BSI) in patients receiving chemotherapy after surgery for colorectal cancer (CRC). Methods: CVCR-BSI was evaluated retrospectively from a database of patients who had received postoperative...

  • Right atrial thrombus: a complication of total parental nutrition in an adult. Chamsi-Pasha, H.; Irving, M.H. // British Medical Journal (Clinical Research Edition);8/1/1987, Vol. 295 Issue 6593, p308 

    Examines the complication of total parenteral nutrition in an adult. Diagnosis of right atrial thrombus from clinical presentation, ventilation-perfusion scan and echocardiogram; Importance of surveillance of central venous catheters with two dimensional echocardiography in detecting thrombi;...

  • Lysine requirement of neonatal piglets receiving total parenteral nutrition as determined by... House, James D.; Pencharz, Paul B.; Ball, Ronald O. // American Journal of Clinical Nutrition;Jan1998, Vol. 67 Issue 1, p67 

    Looks at a study on total parenteral nutrition (TPN) of Yorkshire piglets. Inclusion of the TPN; Information on the assignment of piglets; Definition of the indicator amino acid oxidation technique; Objectives of the experiment; Materials and methodology used for the study; Results of the...

  • Response of glutamine metabolism to glutamine-supplemented parenteral nutrition. van Acker, Bernadette A.C.; Hulsewe, Karel W.E. // American Journal of Clinical Nutrition;Sep2000, Vol. 72 Issue 3, p790 

    Investigates the effects of total parenteral nutrition (TPN) enriched with glutamine dipeptides on glutamine kinetics for eight to ten days. Importance of glutamine for the function of many organ systems; Preoperative benefits of increased glutamine availability during glutamine-enriched TPN in...

  • Acute polymyopathy during total parenteral nutrition. Stewart, Peter M.; Hensley, William J. // British Medical Journal (Clinical Research Edition);12/12/1981, Vol. 283 Issue 6306, p1578 

    Examines the association of acute polymyopathy with total parenteral nutrition. Deficiency state of various nutrients; Cause of high circulating insulin concentrations; Occurrence of acute myopathy after intravenous lipid supplementation.

  • Total parenteral nutrition: value of a standard feeding regimen. Harper, Peter H.; Royle, Gavin T.; Mitchell, Andrew; Greenall, Michael J.; Grant, Andrew; Winsley, Brian; Atkins, Susan M.; Todd, Elizabeth M.; Kettlewell, Michael G.W. // British Medical Journal (Clinical Research Edition);4/23/1983, Vol. 286 Issue 6374, p1323 

    Focuses on the total parenteral nutrition as a standard feeding regimen conducted by a nutrition service in a regional hospital in Great Britain. Citation on the nutritional contents of the regimen; Maintenance in nitrogen balance; Effectiveness in nourishing patients with total nutritional...

  • Phenylalanine requirements determined by using L-[1-14C]phenylalanine in neonatal piglets... House, James D.; Pencharz, Paul B. // American Journal of Clinical Nutrition;Apr97, Vol. 65 Issue 4, p984 

    Investigates the kinetics and requirements of phenylalanine and tyrosine in neonatal piglets receiving total parenteral nutrition. Two-phase linear-regression-crossover model; Estimates of phenylalanine requirement; Difference between phenylalanine intake and oxidation; Inability of...

  • Abstracts.  // American Journal of Clinical Nutrition;Jul97, Vol. 66 Issue 1, p222 

    Presents an abstract of `Outcome in Critically Ill Obese Patients on Total Parenteral Nutrition (TPN),' by M. Ellerbusch and P. Koszyk presented at the 37th annual meeting of the American Association for Clinical Nutrition in Montreal, Canada on July 24 to 26, 1997.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics