TITLE

Intraoperative and Early Postoperative Gastric Intramucosal pH Predicts Morbidity and Mortality after Major Abdominal Surgery

AUTHOR(S)
Thieodoropoulos, George; Lloyd, Larry R.; Cousins, Geoffrey; Pieper, David
PUB. DATE
April 2001
SOURCE
American Surgeon;Apr2001, Vol. 67 Issue 4, p303
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The present study was undertaken to investigate the correlation between the intraoperative and postoperative gastric intramucosal pH (pHi) with important perioperative variables and to explore any potential relationship of the measured phi with the patients' postoperative course. A prospective study was carded out in a group of 48 patients who underwent major abdominal operations over an 8-month period at St. John Hospital and Medical Center. An automated air tonometer was used for gastric phi monitoring. Twenty-eight elective and 20 emergency abdominal operations were performed in 23 men and 25 women. Twenty-six patients (54%) required postoperative hospitalization in the Intensive Care Unit (ICU). Seventeen patients (35%) developed early postoperative complications. The non-ICU and ICU mortality rates were 4.5 and 19.2 per cent respectively. The mean intraoperative phi (pHiOR) and postoperative phi (pHiPO) ranged between 7.03 and 7.58 (7.38 +/- 0.12) and 6.89 and 7.56 (7.35 +/- 0.12) respectively (mean +/- standard deviation). There was a significant decrease of the gastric phi at the first hour intraoperatively compared with the phi after induction to anesthesia (7.44 vs 7.38 +/- 0.14, P < 0.001). Patients who underwent emergent abdominal procedures were characterized by lower pHiOR and pHiPO values (7.43 +/- 0.08 vs 7.30 +/- 0.13 and 7.39 +/- 0.84 vs 7.30 +/- 0.15, P < 0.001 and P < 0.05). Similarly patients who required surgical ICU admission had significantly lower pHiOR and pHiPO measurements (7.3 +/- 0.12 and 7.28 +/- 0.12) compared with the rest (7.46 +/- 0.06 and 7.43 +/- 0.06; P < 0.001). Overall, lower pHiOR and pHiPO values were associated with the occurrence of postoperative complications (P < 0.001), the postoperative mortality (P < 0.001), the requirement for postoperative mechanical ventilator (P < 0.001) and its duration (P < 0.001), longer ICU stay (P < 0.001), and prolonged hospitalization (P < 0.05). Evidence of intraoperative and ear...
ACCESSION #
5181277

 

Related Articles

  • Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients. Tanaka, Aya; Shimono, Ryuichi; Kubo, Hiroyuki; Fujii, Takayuki; Miyatake, Nobuyuki // Pediatric Surgery International;Oct2015, Vol. 31 Issue 10, p911 

    Purpose: This study aimed to evaluate esophageal function before and after antireflux surgery (ARS) in neurologically impaired (NI) patients using 24 h multichannel intraluminal impedance (MII)-pH measurement.Methods: Seven NI patients (age, 0-33 years; median, 13...

  • The Relationship between Gastric Juice Nitrate/Nitrite Concentrations and Gastric Mucosal Surface pH. Hae Kyung Lee; Hyunjung Kim; Hyung-Keun Kim; Young-Seok Cho; Byung-Wook Kim; Sok-Won Han; Lee So Maeng; Hiun-Suk Chae; Hee Na Kim // Yonsei Medical Journal;Nov2012, Vol. 53 Issue 6, p1154 

    Purpose: To investigate gastric juice nitrate/nitrite concentration according to mucosal surface pH extent (area) of gastric corpus intimately contacting the gastric juice. Materials and Methods: We included ninety-nine patients with dyspepsia. To evaluate gastric mucosal surface pH and its...

  • Improvement of the stability under illumination of a-Si:H films elaborated by ion-beam-assisted... Rinnert, H.; Vergnat, M.; Marchal, G.; Burneau, A. // Journal of Applied Physics;1/15/1998, Vol. 83 Issue 2, p1103 

    Focuses on the improvement of the stability under illumination of a-Si: H films elaborated by ion-beam-assisted evaporated by use of a hydrogen-argon plasma. Details on the influence of substrate temperatures; Information on the use of a cryogenerator for the pumping rate of plasma generation...

  • Getting the most out of your soil.  // Good Housekeeping;May98, Vol. 226 Issue 5, p173 

    Compares several methods to obtain the potential of hydrogen ions (pH) of soils. Advantages of mail-in services over do-it-yourself kits.

  • Israelis develop new mini-pH instrument. Lennox-Kerr, Peter // Textile World;Aug93, Vol. 143 Issue 8, p32 

    Reports on Israeli scientists' development of an accurate but economical pH indicator to measure the acidity of tiny samples. Measurement of aqueous and nonaqueous solutions; Production of samples to ten microliters.

  • Tools for Environmental Health. Powitz, Robert W.; Balsamo, James J. // Journal of Environmental Health;Dec2002, Vol. 65 Issue 5, p45 

    Presents information on tools useful to environmental health professionals in monitoring food pH as of December 2002. Features of pen-type pH meters; Accuracy of measuring pH using colorimetric measuring tools; Suggested colorimetric papers to measure pH of liquids such juices, softdrinks and...

  • The Role of Proximal pH Monitoring. Mainie, Inder; Agrawal, Amit; Tutuian, Radu; Castell, Donald O. // American Journal of Gastroenterology;Jul2005, Vol. 100 Issue 7, p1621 

    Presents a letter to the editor about the role of proximal pH monitoring.

  • SWE gives good marks to three industrial pH meters.  // Control Engineering;Jul98, Vol. 45 Issue 9, p87 

    Deals with the three industrial acidity meters. How testing is done; Testing protocols; Instruments and electrodes evaluated; Performance levels.

  • Spectrum science. Dalby, David K. // Science Teacher;Mar93, Vol. 60 Issue 3, p72 

    Presents a method of demonstrating pH, indicators or colors in white light. Materials; Set-up; Step-by-step procedure; Effect of ethanol evaporation from the glass on the experiment; Safety measures.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics