Metastatic Soft Tissue Squamous Cell Carcinoma

Kim, Christina J.; Yeh, Karen A.; Day, Scott
February 2001
American Surgeon;Feb2001, Vol. 67 Issue 2, p111
Academic Journal
Metastatic squamous cell carcinoma of the soft tissue is extremely rare. We report two patients with soft tissue metastasis from squamous cell carcinoma of the cervix in one and scalp in another. Case 1: A 63-year-old black woman with a history of cervical cancer presented with a painful mass over the right scapula. An incisional biopsy revealed squamous cell carcinoma. She underwent radiation treatment followed by wide local excision with en bloc resection and a myocutaneous flap closure. Case 2: A 46-year-old white man with a history of squamous cell carcinoma of the scalp and two kidney transplantations requiring long-term immunosuppression presented with a 2-month history of a left proximal arm mass. Magnetic resonance imaging revealed that the mass was within the triceps muscle and fixed to the humerus. Biopsy revealed squamous cell carcinoma. He underwent a shoulder disarticulation for tumor invasion into the adjacent humerus and neurovascular bundles. The patients remain disease-free at 12 and 8 months, respectively. To our knowledge there are no reports of soft tissue squamous cell carcinoma metastatic from the cervix and only rare cases from the lung, head, and neck. The optimal mode of treatment and prognosis is undefined in these patients because of its rare incidence. Surgery and radiation with curative intent were used.


Related Articles


    To investigate the correlation between Cyclin D1 expression and the clinical staging, tumor cell grading and the lymph node metastasis of non kereatinizing squamous cell cervical cancer. The research design s observational study with cross sectional approach in Gynecologi Oncology Clinic and...

  • Detection of lymph node micrometastases in patients with squamous carcinoma of the head and neck. Ferlito, Alfio; Rinaldo, Alessandra; Devaney, Kenneth; Nakashiro, Koh-ichi; Hamakawa, Hiroyuki // European Archives of Oto-Rhino-Laryngology;Oct2008, Vol. 265 Issue 10, p1147 

    While the significance of large cervical node metastases in patients with head and neck squamous carcinomas is well established, the import of a finding of regional nodal micrometastases (where a micrometastasis is defined as a metastatic deposit greater than 0.2 mm and not greater than 2.0 mm...

  • Colonic metastasis from carcinoma cervix: an unusual cause of intestinal obstruction. Prem, S.; Gangothri, S.; Parthasarathy, V.; Reddy, K. S.; Basu, D. // Southern African Journal of Gynaecological Oncology;2012, Vol. 4 Issue 1, p34 

    The article presents a rare case of colonic metastasis which presents as an intestinal obstruction as a complication from a pelvic radiotherapy for a stage II B squamous cell carcinoma of the cervix in a 36-year-old woman. The patient was treated with concurrent chemo-radiation, and five years...

  • Isolated metastasis to colon from carcinoma cervix. Singla, M.; Singal, R.; Singla, S.; Sahu, P.; Kaur, S.; Goyal, Y. R. // Indian Journal of Cancer;Apr-Jun2011, Vol. 48 Issue 2, p267 

    The article presents a case study of a 48-year female with subacute intestinal obstruction, associated with on and off pain in right hypochondrium, and anorexia of four months duration. The patient undergone a series of examination, which revealed primary squamous cell carcinoma (SCC) of the...

  • Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix. Kanthan, Rani; Senger, Jenna-Lynn B.; Diudea, Dana // World Journal of Surgical Oncology;2010, Vol. 8, p107 

    Introduction: Pulmonary metastasis presenting as lymphangitic carcinomatosis arising from squamous cell carcinoma (SCC) of the cervix is a rare event. Poorly represented in the literature, this event is associated with a) difficulty in accurate diagnosis, b) grave prognosis, and the c) lack of...

  • The relationship between positive peritoneal cytology and the prognosis of patients with FIGO stage I/II uterine cervical cancer. Kuji, Shiho; Hirashima, Yasuyuki; Komeda, Satomi; Tanaka, Aki; Abe, Masakazu; Takahashi, Nobutaka; Takekuma, Munetaka // Journal of Gynecologic Oncology;2014, Vol. 25 Issue 2, p90 

    Objective: The purpose of this study was to assess whether peritoneal cytology has prognostic significance in uterine cervical cancer. Methods: Peritoneal cytology was obtained in 228 patients with carcinoma of the uterine cervix (International Federation of Gynecology and Obstetrics [FIGO]...

  • Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern. Hiroshima, Yukihiko; Zhang, Yong; Zhang, Nan; Maawy, Ali; Mii, Sumiyuki; Yamamoto, Mako; Uehara, Fuminari; Miwa, Shinji; Yano, Shuya; Murakami, Takashi; Momiyama, Masashi; Chishima, Takashi; Tanaka, Kuniya; Ichikawa, Yasushi; Bouvet, Michael; Murata, Takuya; Endo, Itaru; Hoffman, Robert M. // PLoS ONE;Feb2015, Vol. 10 Issue 2, p1 

    Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often metastatic and treatment resistant with no standard treatment protocol. Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) nude mouse model with the technique of surgical orthotopic...

  • Metastatic Squamous Cell Carcinoma of the Cervix Presenting as an Adnexal Neoplasm. Katsnelson, Marina; Toll, Adam; Biroschak, Julianne; Rosenblum, Norman G. // Clinical Ovarian Cancer;Jun2011, Vol. 4 Issue 1, p47 

    Cervical cytology in the form of a Papanicolaou test has been an invaluable tool in reducing the worldwide incidence of invasive cervical cancer. Human papilloma virus (HPV) 16 is the most common genotype detected in both cervical intraepithelial neoplasia 3/carcinoma in-situ and invasive...

  • Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. Green, J.; Berrington de Gonzalez, A.; Sweetland, S.; Beral, V.; Chilvers, C.; Crossley, B.; Deacon, J.; Hermon, C.; Jha, P.; Mant, D.; Peto, J.; Pike, M.; Vessey, M.P. // British Journal of Cancer;12/1/2003, Vol. 89 Issue 11, p2078 

    We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell carcinoma and 923 population controls. The...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics