Porcelain Gallbladder Is Not Associated with Gallbladder Carcinoma

Towfigh, Shirin; McFadden, David W.; Thompson Jr., Jesse E.; Tompkins, Ronald K.; Chandler, Charles; Hines, Oscar J.; Cortina, Galen R.
January 2001
American Surgeon;Jan2001, Vol. 67 Issue 1, p7
Academic Journal
The surgical management of porcelain gallbladder is based on studies performed in 1931 and 1962, which indicated a correlation between porcelain gallbladder and carcinoma. We sought to evaluate the characteristics of patients with porcelain gallbladder and the risk for gallbladder carcinoma. The medical records of 10,741 cholecystectomies performed between 1955 and 1998 were reviewed and recorded. The pathology slides were evaluated for evidence of calcification and gallbladder carcinoma. Fifteen (0.14%) of 10,741 specimens were porcelain gallbladders. Ten patients (67%) had symptoms suggestive of biliary colic or cholecystitis. Five (33%) were asymptomatic and diagnosed incidentally. All specimens demonstrated chronic cholecystitis and partial calcification of the gallbladder wall. Nine (60%) had cholelithiasis. None had gallbladder carcinoma by recent review of pathologic material. During this same period 88 (0.82%) patients had gallbladder carcinoma, none of which showed calcification of the wall. This report represents the largest modern review of porcelain gallbladders. No carcinoma was identified among patients with porcelain gallbladder. In addition no patient with gallbladder carcinoma had calcified gallbladder. With a better understanding of the natural history of the porcelain gallbladder the current management of these patients may change.


Related Articles

  • An Extrahepatic Bile Duct Metastasis From a Gallbladder Cancer Mimicking Mirizzi's Syndrome. Akiyama, Hiroto; Sato, Tatsuro; Toyoda, Sumio; Yamada, Hirochika // American Journal of Gastroenterology;Feb1999, Vol. 94 Issue 2, p508 

    We report a case of an extrahepatic bile duct metastasis from it gallbladder cancer that mimicked Mirizzi's syndrome on cholangiography. A 67-yr-old woman was admitted to our hospital with a diagnosis of acute calculous cholecystitis. As obstructive jaundice developed after the admission,...

  • INCIDENTAL GALLBLADDER CARCINOMA IN PATIENTS UNDERGOING CHOLECYSTECTOMY FOR CHOLELITHIASIS; A CLINICOPATHOLOGICAL STUDY. Munshi, Sayar Kumar; Pal, Sabuj; Ray, Debabrata; Sarkar, Niladri; Chowdhury, Debangshu Bhanja // Journal of Surgical Arts / Cerrahi Sanatlar Dergisi;2015, Vol. 8 Issue 2, p41 

    Gallbladder carcinoma is the most common carcinoma of the biliary tract. Although it is a relatively rare disease, it is a highly aggressive malignancy. The prevalence of carcinoma in the gallbladder is greatly variable in different parts of the world. Gallbladder carcinoma is diagnosed...

  • Malignant melanoma of the gallbladder: a report of two cases and review of the literature. Samplaski, Mary K.; Rosato, Ernest L.; Witkiewicz, Agnes K.; Mastrangelo, Michael J.; Berger, Adam C. // Journal of Gastrointestinal Surgery;Jun2008, Vol. 12 Issue 6, p1123 

    Melanoma metastatic to the gallbladder is rare. When present, it is often part of a widespread complex of metastases. Primary gallbladder melanomas are also extremely rare and can sometimes be difficult to distinguish from metastatic lesions. The optimal treatment for malignant melanoma of the...

  • Cancer of the gallbladder - own experience. Gryko, M.; Dawidziuk, T.; Sawicka, E.; Cepowicz, D.; Kamocki, Z.; Masiulaniec, P.; Kędra, B. // Progress in Health Sciences;Jun2014, Vol. 4 Issue 1, p153 

    Gallbladder cancer is a relatively rare cancer of the gastrointestinal tract, most commonly detected (approximately 95% of cases) in the most advanced clinical stage IV and burdened with high mortality rate. This is mainly due to the nonspecific symptoms in the early stages of the disease. The...

  • GALLBLADDER CANCERS (GBCS) - RARE ENTITIES. Donato, Paradiso; Emőke, Fülöp; Simona, Pataki // Acta Medica Marisiensis;2019 Supplement, Vol. 65, p103 

    Background: Gallbladder cancers are rare entities (0.7% of all tumors), mostly of epithelial origin, more common in women than men, due to the higher incidence of gallstones in women. Usually diagnosed incidentally in advanced stages, due to insidous onset of nonspecific symptoms, GBCs have a...

  • Is Microscopic Examination of All Cholecystectomy Specimens Necessary? Newell, Christopher; Barkwell, Teresa; Newell, Ken J. // Canadian Journal of Pathology;2010, Vol. 2 Issue 2, p22 

    Cholecystectomy for gallstone disease is a common procedure in Canadian hospitals. Gallbladder cancer is a rare malignancy that has a poor prognosis. The objective of this study was to determine if the selective microscopic examination of cholecystectomy specimens would be feasible in a Canadian...

  • CANCER OF THE GALLBLADDER. Milner, Leo R. // American Journal of Gastroenterology;May1963, Vol. 39 Issue 5, p480 

    Presents information on gallbladder cancer. Association of gallbladder cancer with gallstones; Incidence of gallbladder cancer in the general autopsy population at the Boston City Hospital; Comments from surgeons on the relationship between gallbladder cancer and gallstones.

  • Incidenca i hirurÅ¡ki tretman karcinoma žučne kese. Rifatbegović, Zijah; Mešić, Dešo; Ljuca, Farid; Zildžić, Muharem; Morankić, Mirza // Medicinski Arhiv;2007, Vol. 61 Issue 1, p30 

    The gallbladder cancer is the most common primary cancer of the hepatobiliary system, and ranks fifth of the cancers of the gastrointestinal system. It is accidentally found in 1-3 % of patients with gallstone disease, and in 0,5-2,4 % on postmortem exam. Goal: Show the incidence, clinical...

  • Ä°nsidental safra kesesi skuamöz hücreli karsinomu. Böyük, Abdullah; Solmaz, Özgen Arslan; Mengücük, Mehmet Emin; Banlı, Oktay // Turkish Journal of Surgery / Ulusal Cerrahi Dergisi;2010, Vol. 26 Issue 1, p43 

    Despite their low incidence, gallbladder cancers have a poor prognosis. About 1.4% to 10.6% of these cancers consist of cancers with squamous differentiation. Although rare, cancers with squamous differentiation have a more aggressive course than the other gallbladder cancers. We present here a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics