Decolonization of nostrils and skin of nasal carriers of S. aureus at admission prevented hospital-associated infection

Golan, Yoav
May 2010
ACP Journal Club;5/18/2010, Vol. 152 Issue 5, p8
Academic Journal
The article reports on a study related to the identification of nasal carriers of Staphylococcus (S.) aureus and decolonization of nostrils in preventing hospital-associated S. aureus infection. As stated, 918 adults were examined on rapid screening for nasal carriage of S. aureus at hospital admission in Netherlands. However, it concludes that decolonization of the nostrils with mupirocin ointment and chlorhexidine soap prevented hospital-associated infection with S. aureus.


Related Articles

  • 2. Fusidic acid in skin and soft-tissue infections. Long, Barry H. // Acta Dermato-Venereologica;2008 Supplement, p14 

    Topical antibacterial therapy is an important component in managing skin and soft-tissue infections (SSTIs). Fusidic acid, a narrow-spectrum antibiotic active against Staphylococcus aureus, has shown good skin permeability and low allergenic potential. The resistance rate in S. aureus remains...

  • The Current State of Screening and Decolonization for the Prevention of Staphylococcus aureus Surgical Site Infection After Total Hip and Knee Arthroplasty. Weiser, Mitchell C.; Moucha, Calin S. // Journal of Bone & Joint Surgery, American Volume;9/2/2015, Vol. 97 Issue 17, p1449 

    The article focuses on the prevention of Staphylococcus aureus surgical site infection after total hip and knee arthroplasties through medical screening and nasal decolonization. Topics discussed include the antibiotic therapy for patients undergoing the surgical procedures, the effectiveness of...

  • Mupirocin-Based Decolonization of Staphylococcus aureus Carriers in Residents of 2 Long-Term Care Facilities: A Randomized, Double-Blind, Placebo-Controlled Trial. Mody, Lona; Kauffman, Carol A.; McNeil, Shelly A.; Galecki, Andrzej T.; Bradley, Suzanne F. // Clinical Infectious Diseases;12/1/2003, Vol. 37 Issue 11, p1467 

    Mupirocin has been used in nursing homes to prevent the spread of methicillin-resistant Staphylococcus aureus (MRSA), despite the lack of controlled trials. In this double-blind, randomized study, the efficacy of intranasal mupirocin ointment versus that of placebo in reducing colonization and...

  • Do topical antibiotics improve wound healing? Diehr, Sabina; Hamp, Andrew; Jamieson, Barbara // Journal of Family Practice;Feb2007, Vol. 56 Issue 2, p140 

    The article discusses the effect of topical antibiotics in the improvement of wound healing. According to randomized controlled trials, the use of topical triple-antibiotic ointments decreases infection rates in minor contaminated wounds. In the treatment of secondarily infected minor wounds and...

  • Anti-staphylococcal β-lactam Antibiotics Potentiate Daptomycin Activity vs. MRSA. Winslow, Dean L. // Infectious Disease Alert;Sep2011 Supplement, p27 

    Seven patients were identified when DAP-ASBL therapy was used to eradicate persistent MRSA bacteremia. Isolates from 3 patients were available for in vitro study. Standard minimum inhibitory concentrations (MICs) were determined and time-kill curves in Mueller-Hinton broth media were performed...

  • Community-associated methicillin-resistant Staphylococcus aureus: prevalence in skin and soft tissue infections at emergency departments in the Greater Toronto Area and associated risk factors. Adam, Heather J.; Allen, Vanessa G.; Currie, Andrea; McGeer, Allison J.; Simor, Andrew E.; Richardson, Susan E.; Louie, Lisa; Willey, Barbara; Rutledge, Tim; Lee, Jacques; Goldman, Ran D.; Somers, Andrea; Ellis, Paul; Sarabia, Alicia; Rizos, John; Borgundvaag, Bjug; Katz, Kevin C. // CJEM: Canadian Journal of Emergency Medicine;Sep2009, Vol. 11 Issue 5, p439 

    Objective: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), which is caused primarily by the Canadian methicillin-resistant Staphylococcus aureus-10 (CMRSA-10) strain (also known as the USA300 strain) has emerged rapidly in the United States and is now emerging in...

  • Home Invasion. Sachs, Jessica Snyder // Best Life;Oct2008, Vol. 5 Issue 8, p60 

    The article offers tips on protecting one's family and children from methicillin-resistant Staphylococcus aureus infection. When antibiotics are necessary, ask for narrow spectrum antibiotics, which are less disruptive of the body's good bacteria. Teaching children good hygiene is the single...

  • Clinical Effectiveness of Mupirocin for Preventing Staphylococcus aureus Infections in Nonsurgical Settings: A Meta-analysis. Nair, Rajeshwari; Perencevich, Eli N.; Blevins, Amy E.; Goto, Michihiko; Nelson, Richard E.; Schweizer, Marin L. // Clinical Infectious Diseases;3/1/2016, Vol. 62 Issue 5, p618 

    A systematic literature review and meta-analysis was performed to identify effectiveness of mupirocin decolonization in prevention of Staphylococcus aureus infections, among nonsurgical settings. Of the 15 662 unique studies identified up to August 2015, 13 randomized controlled trials, 22...

  • Synergistic Antibacterial and Antibiotic Effects of Bisbenzylisoquinoline Alkaloids on Clinical Isolates of Methicillin-Resistant Staphylococcus Aureus (MRSA). Guo-Ying Zuo; Yang Li; Tao Wang; Jun Han; Gen-Chun Wang; Yun-Ling Zhang; Wei-Dong Pan // Molecules;Dec2011, Vol. 16 Issue 12, p9819 

    The antibacterial activity of two bisbenzylisoquinoline alkaloids, tetrandrine (Tet) and demethyltetrandrine (d-Tet), alone and in combination with the antibiotics ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) against 10 clinical isolates of staphylococcal...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics