Pneumococcal vaccine reduced pneumococcal pneumonia and associated mortality
- Capsules, Clones, and Curious Events: Pneumococcus under Fire from Polysaccharide Conjugate Vaccine. Long, Sarah S. // Clinical Infectious Diseases;7/1/2005, Vol. 41 Issue 1, p30
The article focuses on the pneumococcal conjugate vaccine (PCV) containing streptococcus pneumoniae serotypes. It was found that various cases of invasive disease due to streptococcus pneumoniae serotypes occurred in children who were administered PCV. But now studies have shown that there is a...
- Initial and Subsequent Response to Pneumococcal Polysaccharide and Protein-Conjugate Vaccines Administered Sequentially to Adults Who Have Recovered from Pneumococcal Pneumonia. Musher, Daniel M.; Rueda, Adriana M.; Nahm, Moon H.; Graviss, Edward A.; Rodriguez-Barradas, Maria C. // Journal of Infectious Diseases;10/1/2008, Vol. 198 Issue 7, p1019
Background. Controversy persists over the benefits of pneumococcal polysaccharide vaccine (PPV) for adults at high risk for pneumococcal disease. We studied PPV, protein-conjugate pneumococcal vaccine (PCV), and immunologic "priming" with PCV followed by "boosting" with PPV in adults who had...
- Capsular Serotype-Specific Attack Rates and Duration of Carriage of Streptococcus pneumoniae in a Population of Children. Sleeman, Karen L.; Griffiths, David; Shackley, Fiona; Diggle, Linda; Gupta, Sunetra; Maiden, Martin C.; Moxon, E. Richard; Crook, Derrick W.; Peto, Timothy E. A. // Journal of Infectious Diseases;9/1/2006, Vol. 194 Issue 5, p682
Background. The relative invasiveness rates (attack rates) of Streptococcus pneumoniae of different capsular serotypes in children are not known. Estimates of capsular serotype invasiveness (designated â€˜invasive odds ratiosâ€™) that are based on cross-sectional prevalence carriage...
- Serotype Distribution in Non-Bacteremic Pneumococcal Pneumonia: Association with Disease Severity and Implications for Pneumococcal Conjugate Vaccines. Benfield, Thomas; Skovgaard, Marlene; Schønheyder, Henrik Carl; Knudsen, Jenny Dahl; Bangsborg, Jette; Østergaard, Christian; Slotved, Hans-Christian; Konradsen, Helle Bossen; Thomsen, Reimar Wernich; Lambertsen, Lotte // PLoS ONE;Aug2013, Vol. 8 Issue 8, p1
Background:There is limited knowledge of serotypes that cause non-bacteremic pneumococcal pneumonia (NBP). Here we report serotypes, their associated disease potential and coverage of pneumococcal conjugate vaccines (PCV) in adults with NBP and compare these to bacteremic pneumonia (BP)....
- Pneumococcal infection in children with no spleen. // Archives of Disease in Childhood;Nov2002, Vol. 87 Issue 5, p433
Overwhelming infection remains a problem for children who have no spleen either because they were born without one or because they have gone undergone splenectomy. They are at risk from all encapsulated bacterial pathogens but more than half of invasive infections in these children are caused by...
- The Pneumococcus at the Millennium: Not Down, Not Out. Austrian, Robert // Journal of Infectious Diseases;3/15/99 Supplement 2, Vol. 179, pS338
Focuses on the biological importance of the bacterium Streptococcus pneumoniae. Diseases caused by the bacterium; Increase in the number of pneumococcal isolates resistant to antimicrobial agents; Relevance of pneumococcal vaccines.
- Pneumococcal Conjugate Vaccine (Prevnarâ„¢Use of the US tradename is for product identification purposes only, and does not imply endorsement.; PNCRM7): A Review of its Use in the Prevention of Streptococcus pneumoniae Infection. Darkes, Malcolm J.M.; Plosker, Greg L. // Pediatric Drugs;2002, Vol. 4 Issue 9, p609
Reviews the use of pneumococcal conjugate vaccine in the prevention of Streptococcus pneumoniae infection. Overview of Streptococcus pneumoniae and the role of polysaccharide vaccines; Immunogenicity; Protective efficacy; Tolerability; Dosage and administration.
- Pneumococcal Vaccine Recommendation. // Annals of Internal Medicine;Feb82, Vol. 96 Issue 2, p206
Discusses the recommendations of the American College of Physicians regarding the use of the pneumococcal vaccine against diseases caused by Streptococcus pneumoniae. Patients qualified for receiving the vaccine; Quantity of data on the correlation of pneumococcal bacteremia with age; Type of...
- Infection. // Africa Health;May2013, Vol. 35 Issue 4, p57
The article focuses on a trial conducted on 47369 children for analyzing the use of seven-valent pneumococcal vaccine in reducing rates of invasive pneumococcal disease.