Relationship between soy and isoflavone intake and periodontal disease: the Freshmen in Dietetic Courses Study II

Rosvall, Maria; Chaix, Basile; Lynch, John; Lindström, Martin; Merlo, Juan
January 2008
BMC Public Health;2008, Vol. 8 Issue 1, p39
Academic Journal
Background: Much research has shown that soy products inhibited various diseases. However, no published studies have examined the effects of consumption of soy and isoflavones on periodontal disease. The aim of this study was to investigate whether soy and isoflavone intake is associated with the prevalence of periodontal disease. Methods: The subjects were 3956 Japanese female students, aged 18 to 22 years, who were taking a dietetic course. Periodontal disease was defined as present when a subject reported diagnosis of the disorder by a dentist. Information on dietary factors was collected using a validated diet history questionnaire. Logistic regression analysis was used to estimate the odds ratios and their confidence intervals of periodontal disease. Adjustment was made for cigarette smoking, toothbrushing frequency, region of residence, and body mass index. Results: The prevalence of periodontal disease was 8.0%. Intake of total soy product and tofu was independently associated with a decreased prevalence of periodontal disease; multivariate odds ratios in comparison of the highest with the lowest quintile were 0.68 and 0.68, respectively (95% confidence intervals = 0.47-0.97 and 0.47-0.98, P for trend = 0.01 and 0.004, respectively). A significant inverse dose-response relationship between the intake of isoflavones and the prevalence of periodontal disease was observed, although the difference in the adjusted odds ratio between the extreme quintiles was of borderline significance (P for trend = 0.04). There were no measurable dose-response relationships between consumption of tofu products, fermented soybeans, boiled soybeans, miso, or miso soup and the prevalence of periodontal disease. Conclusion: Our findings suggest that soy and isoflavone intake may decrease the likelihood of periodontal disease. Further investigations with objective measures for periodontal disease are needed to confirm our findings.


Related Articles

  • Multivariate Statistical Modeling of the Factors Affecting Oral Health Disease - A Periodontal Disease. Javali, S. B. // Romanian Statistical Review;2011, Issue 1, p66 

    Periodontal disease is the most common oral diseases that affect mankind and it occupies a prominent role in deciding the oral health status through out the world. In this study, an effort has been made to determine the most likely factors affecting periodontal disease and to select a meticulous...

  • Third molars may have a negative impact on periodontal health. Smart, Graham J // Evidence-Based Dentistry;Dec2005, Vol. 6 Issue 4, p95 

    DesignThis was a cross-sectional study.Materials and methodsData were within a cohort study obtained between 1996 and 1999 on 6793 people of 52–74 years of age from the dental substudy of the Atherosclerosis Risk in Communities Study. The main independent variable was presence or absence...

  • Relationship among impaired fasting glucose and diabetes and periodontal disease. Ji-Hye Park // Journal of the Korea Academia-Industrial Cooperation Society;2015, Vol. 16 Issue 1, p389 

    This study examined the relationships among impaired fasting glucose (IFG), diabetes and periodontal disease. The data from 10,856 adults (aged over 19 years) was derived from the Fifth Korean National Health and Nutrition Examination Survey, which was conducted in 2010 and 2012. Adjusting the...

  • Periodontitis - the new caries? Hughes, Francis // British Dental Journal;10/24/2014, Vol. 217 Issue 8, p387 

    An introduction is presented in which the editor discusses various reports within the issue on topics including periodontal diseases and medicine, relationship between periodontitis and systemic health, and prevalence of periodontitis in a Roman-Britain population

  • Maternal Periodontal Disease and Risk of Preeclampsia: A Case–Control Study. Lohsoonthorn, Vitool; Kungsadalpipob, Kajorn; Chanchareonsook, Prohpring; Limpongsanurak, Sompop; Vanichjakvong, Ornanong; Sutdhibhisal, Sanutm; Sookprome, Chulamanee; Wongkittikraiwan, Nopmanee; Kamolpornwijit, Wiboon; Jantarasaengaram, Surasak; Manotaya, Saknan; Siwawej, Vatcharapong; Barlow, William E.; Fitzpatrick, Annette L.; Williams, Michelle A. // American Journal of Hypertension;Apr2009, Vol. 22 Issue 4, p457 

    BackgroundWe examined whether pregnant women with periodontal disease have an increased risk of preeclampsia, and we empirically evaluated the extent to which associations between periodontal disease and preeclampsia are dependent upon diagnostic criteria used to define periodontal disease...

  • Rheumatoid Arthritis among Periodontitis Patients in Baddi Industrial Estate of Himachal Pradesh, India: A Cross Sectional Study. DEV, YASH PAUL; KHULLER, NITIN; BASAVARAJ, PATTHI; SURESH, G. // Journal of Clinical & Diagnostic Research;Oct2013, Vol. 7 Issue 10, p2334 

    Aim: To determine whether there is a relationship between periodontal disease and rheumatoid arthritis. Methods: A total of 1520 (852 - periodontal group; 668 - general group) individuals of 30-70 years age group and residents of Baddi industrial estate in Himachal Pradesh, India, were assessed...

  • Guidelines: Sound principles. Richards, W. // British Dental Journal;1/23/2015, Vol. 218 Issue 2, p44 

    A letter to the editor is presented on treating periodontal disease.

  • Letters to the Editor. Pagare, Nikhil; Varma, Sudhir R.; Kanungo, N. // Clinical Dentistry (0974-3979);Aug2015, Vol. 9 Issue 8, p6 

    Several letters to the editor are presented in response to articles in previous issues including "Salivaomics as an emerging diagnostic tool for periodontal diseases" by Dr. Pooja P. Wattamwar in the January 2015 issue and "Compo-Liga-Comp" by Dr Maheshwara MV in the February 2015 issue.

  • pocket, gingival. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p616 

    An encyclopedia entry for "gingival pocket," a feature of marginal periodontitis, is presented.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics