Addition of Severe Combined Immunodeficiency as a Contraindication for Administration of Rotavirus Vaccine

June 2010
MMWR: Morbidity & Mortality Weekly Report;6/11/2010, Vol. 59 Issue 22, p687
The article reports on the efforts done by pharmaceutical companies in 2010 to address the cases of vaccine-acquired rotavirus infection in infants with severe combined immunodeficiency (SCID) ensuing the administration of rotavirus vaccine. The prescribing information and patient labeling for the pentavalent rotavirus vaccine and monovalent rotavirus vaccine products of GlaxoSmithKline Biologicals and Merck & Co. have been revised. Rotavirus vaccine was launched in the U.S. in 2006.


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