Lung cancer mortality in towns near paper, pulp and board industries in Spain: a point source pollution study

Monge-Corella, Susana; García-Pérez, Javier; Aragonés, Nuria; Pollán, Marina; Pérez-Gómez, Beatriz; López-Abente, Gonzalo
January 2008
BMC Public Health;2008, Vol. 8 Issue 1, p288
Academic Journal
Background: This study sought to ascertain whether there might be excess lung cancer mortality among the population residing in the vicinity of Spanish paper and board industries which report their emissions to the European Pollutant Emission Register (EPER). Methods: This was an ecological study that modelled the Standardised Mortality Ratio (SMR) for lung cancer in 8073 Spanish towns over the period 1994-2003. Population exposure to industrial pollution was estimated on the basis of distance from town of residence to pollution source. An exploratory, near-versus-far analysis was conducted, using mixed Poisson regression models and an analysis of the effect of municipal proximity within a 50-kilometre radius of each of the 18 installations. Results: Results varied for the different facilities. In two instances there was an increasing mortality gradient with proximity to the installation, though this was exclusively observed among men. Conclusion: The study of cancer mortality in areas surrounding pollutant foci is a useful tool for environmental surveillance, and serves to highlight areas of interest susceptible to being investigated by ad hoc studies. Despite present limitations, recognition is therefore due to the advance represented by publication of the EPER and the study of pollutant foci.


Related Articles

  • Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study. López-Cima, María Felicitas; García-Pérez, Javier; Pérez-Gómez, Beatriz; Aragonés, Nuria; López-Abente, Gonzalo; Tardón, Adonina; Pollán, Marina // International Journal of Health Geographics;2011, Vol. 10 Issue 1, p10 

    Background: Asturias, an Autonomous Region in Northern Spain with a large industrial area, registers high lung cancer incidence and mortality. While this excess risk of lung cancer might be partially attributable to smoking habit and occupational exposure, the role of industrial and urban...

  • LncRNA LCPAT1 Mediates Smoking/ Particulate Matter 2.5-Induced Cell Autophagy and Epithelial-Mesenchymal Transition in Lung Cancer Cells via RCC2. Lin, Hongyan; Zhang, Xiaohong; Feng, Nannan; Wang, Ruoyang; Zhang, Weituo; Deng, Xiaobei; Wang, Yu; Yu, Xiao; Ye, Xiaofei; Li, Lei; Qian, Ying; Yu, Herbert; Qian, Biyun // Cellular Physiology & Biochemistry (Karger AG);Jul2018, Vol. 47 Issue 3, p1244 

    Background/Aims: Ecological studies have shown that air pollution and prevalence of cigarette smoking are positively correlated. Evidence also suggests a synergistic effect of cigarette smoking and PM2.5 exposure (Environmental Particulate Matter ≤ 2.5 µm in diameter) on...

  • Mortalidad por cáncer de pulmón en México de 1990 a 2016: efecto edad-periodo-cohorte. Rojas-Martínez, Rosalba; Escamilla-Núñez, Consuelo; Meza, Rafael; Vázquez-Salas, Ruth Argelia; Zárate-Rojas, Emiliano; Lazcano-Ponce, Eduardo // Salud Pública de México;May/Jun2019, Vol. 61 Issue 3, p230 

    Objective. To update information on the mortality trend due to lung cancer in Mexico from 1990 to 2016. Materials and methods. Age-adjusted rates were obtained using the direct method. The percentage of annual change in the mortality of lung cancer was obtained through joinpoint analysis at the...

  • Trends in lung cancer mortality in South Africa: 1995-2006. Bello, Braimoh; Fadahun, Olufolawajimi; Kielkowski, Danuta; Nelson, Gill // BMC Public Health;2011, Vol. 11 Issue 1, p209 

    Background: Cancer remains a major cause of morbidity and mortality worldwide. In developing countries, data on lung cancer mortality are scarce. Methods: Using South Africa's annual mortality and population estimates data, we calculated lung cancer agestandardised mortality rates for the period...

  • Journal abstracts.  // Palliative Medicine;1999, Vol. 13 Issue 2, p173 

    Presents an abstract of the paper `Is Quality of Life Predictive of the Survival of Patients With Advanced Nonsmall Cell Lung Carcinoma?,' by J.E. Herndon, S. Fleishman et al, published in the `Cancer' journal. Measurement of relationship between quality of life and survival of patients with...

  • Lung cancer mortality reduction by LDCT screening—Results from the randomized German LUSI trial. Becker, Nikolaus; Motsch, Erna; Trotter, Anke; Heussel, Claus P.; Dienemann, Hendrik; Schnabel, Philipp A.; Kauczor, Hans‐Ulrich; Maldonado, Sandra González; Miller, Anthony B.; Kaaks, Rudolf; Delorme, Stefan // International Journal of Cancer;Mar2020, Vol. 146 Issue 6, p1503 

    In 2011, the U.S. National Lung Cancer Screening Trial (NLST) reported a 20% reduction of lung cancer mortality after regular screening by low‐dose computed tomography (LDCT), as compared to X‐ray screening. The introduction of lung cancer screening programs in Europe awaits...

  • Canadian Individual Risks of Radon-induced Lung Cancer for Different Exposure Profiles. Chen, Jing // Canadian Journal of Public Health;Sep/Oct2005, Vol. 96 Issue 5, p360 

    Background: Indoor radon has been determined to be the second leading cause of lung cancer after tobacco smoking. There is an increasing need among radiation practitioners to have numerical values of lung cancer risks for men and women, ever-smokers and never smokers exposed to radon in homes....

  • TWIST1 a New Determinant of Epithelial to Mesenchymal Transition in EGFR Mutated Lung Adenocarcinoma. Pallier, Karine; Cessot, Anatole; Côté, Jean-Francois; Just, Pierre-Alexandre; Cazes, Aurélie; Fabre, Elizabeth; Danel, Claire; Riquet, Marc; Devouassoux-Shisheboran, Mojgan; Ansieau, Stéphane; Puisieux, Alain; Laurent-Puig, Pierre; Blons, Hélène // PLoS ONE;Jan2012, Vol. 7 Issue 1, p1 

    Metastasis is a multistep process and the main cause of mortality in lung cancer patients. We previously showed that EGFR mutations were associated with a copy number gain at a locus encompassing the TWIST1 gene on chromosome 7. TWIST1 is a highly conserved developmental gene involved in...

  • Lower rates of cancer and all-cause mortality in an Adventist cohort compared with a US Census population. Fraser, Gary E.; Cosgrove, Candace M.; Mashchak, Andrew D.; Orlich, Michael J.; Altekruse, Sean F. // Cancer (0008543X);Mar2020, Vol. 126 Issue 5, p1102 

    Background: Previous research suggests that Adventists, who often follow vegetarian diets, live longer and have lower risks for many cancers than others, but there are no national data and little published comparative data for black subjects.Methods: This study compared...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics