Characterization of dielectric barrier electrospray ionization for mass spectrometric detection

Stark, Ann Kathrin; Schilling, Michael; Janasek, Dirk; Franzke, Joachim
July 2010
Analytical & Bioanalytical Chemistry;Jul2010, Vol. 397 Issue 5, p1767
Academic Journal
A novel electrospray interface is presented which induces an electric field by dielectric polarization through a non-conductive barrier. Therefore, a square-wave high-voltage signal is applied. This technique allows mass spectrometric measurements in the positive as well as in the negative mass spectrometry mode without changing the polarity of the potential applied, and it decreases the risk of undesired discharges, induced by high electric currents. The applicability of this technique is demonstrated by mass spectrometric determination of reserpine.


Related Articles

  • Precise and accurate uranium isotope analysis by modified total evaporation using 10 ohm current amplifiers. Trinquier, A.; Komander, P. // Journal of Radioanalytical & Nuclear Chemistry;Mar2016, Vol. 307 Issue 3, p1927 

    This study presents analytical advances in thermal ionization mass spectrometry for uranium isotope analysis involving minor isotopes. The potential of 10 ohm current amplifiers for detecting minor isotope ion beams down to the 10 kcps range during modified total evaporation analyses is assessed...

  • Electronic coupling and scaling effects during dielectric barrier electrospray ionization. Stark, A. K.; Meyer, C.; Kraehling, T.; Jestel, G.; Marggraf, U.; Schilling, M.; Janasek, D.; Franzke, J. // Analytical & Bioanalytical Chemistry;Jun2011, Vol. 400 Issue 2, p561 

    The mechanism of the previously published technique of dielectric barrier electrospray ionization (DB-ESI) was investigated in more detail. Two independent current signals occurring during the DB-ESI could be explained and allocated to sub-processes. The modulated shape of the HV signal, the...

  • Electrospray Ionization for Mass Spectrometry.  // LC-GC North America;Feb2012, Vol. 30 Issue 2, p182 

    The article discusses on electrospray ionization (ESI) for mass spectrometry and its processes. It says that the first stage of EIS is the production of charged eluent droplets at the tip of sprayer through using electric field. It mentions that whole solvent desolvation occurs during the...

  • An electrosprayed coating process for fabricating hemispherical PMMA droplets for an optical diffuser. Seunghyun Ahn; GeunHyung Kim // Applied Physics A: Materials Science & Processing;Oct2009, Vol. 97 Issue 1, p125 

    A modified electrospraying process is proposed for fabricating uniform microsized poly(methyl methacrylate) (PMMA) hemispherical droplets on poly(ethylene terephthalate) films for use as optical diffusers. In this process, an electrode controlled by an electric field is attached to a rotating...

  • Structures and reactions of biomolecular ions produced with electrospray ionization. Nonose, S.; Iwaoka, S.; Tanaka, H.; Okai, N.; Shibakusa, T.; Fuke, K. // European Physical Journal D -- Atoms, Molecules, Clusters & Opti;Jun2003, Vol. 24 Issue 1-3, p335 

    Photo-induced reaction of [Fe(III)-protoporphyrin]+ (hemin+) ions solvated with dimethylsulfoxide (DMSO) is investigated by using a tandem mass spectrometer with electrospray ionization. We measure the photodissociation yields of mass-selected hemin+(DMSO)n clusters for n = 0-3. The mass spectra...

  • Derivatization for Ultratrace Quantitative Analysis Using HPLC-ESI-MS. Schug, Kevin A. // LC-GC North America;Apr2013, Vol. 31 Issue 4, p334 

    A blog related to the derivatization technique electrospray ionization (ESI) is presented.

  • Erratum to: Mechanical ion gate for electrospray-ionization ion-mobility spectrometry. Li Zhou; Collins, David C.; Lee, Edgar D.; Rockwood, Alan L.; Lee, Milton L. // Analytical & Bioanalytical Chemistry;Oct2010, Vol. 398 Issue 4, p1833 

    A correction to the article "Mechanical Ion Gate for Electrospray-Ionization Ion-Mobility Spectrometry" that was published in the online version of the journal on August 14, 2010 issue is presented.

  • Mass analysis of receptor?DNA complexes. DeWitt, Natalie // Nature Biotechnology;Dec99, Vol. 17 Issue 12, p1150 

    Focuses on the use of electrospray ionization mass spectrometry (ESI-MS) in the study of protein complexes. Use of ESI-MS in the analysis of the effect of ligands on heterodimerization of full-length vitamin D and retinoid X receptors.

  • Combined use of ESI�QqTOF-MS and ESI�QqTOF-MS/MS with mass-spectral library search for qualitative analysis of drugs. Pavlic, Marion; Libiseller, Kathrin; Oberacher, Herbert // Analytical & Bioanalytical Chemistry;Oct2006, Vol. 386 Issue 1, p69 

    The potential of the combined use of ESI�QqTOF-MS and ESI�QqTOF-MS/MS with mass-spectral library search for the identification of therapeutic and illicit drugs has been evaluated. Reserpine was used for standardizing experimental conditions and for characterization of the performance...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics