Fabrication and mechanical properties of PLLA/PCL/HA composites via a biomimetic, dip coating, and hot compression procedure

Charles, L. F.; Shaw, M. T.; Olson, J. R.; Wei, M.
June 2010
Journal of Materials Science: Materials in Medicine;Jun2010, Vol. 21 Issue 6, p1845
Academic Journal
Currently, the bone-repair biomaterials market is dominated by high modulus metals and their alloys. The problem of stress-shielding, which results from elastic modulus mismatch between these metallic materials and natural bone, has stimulated increasing research into the development of polymer-ceramic composite materials that can more closely match the modulus of bone. In this study, we prepared poly( l-lactic acid)/hydroxyapatite/poly(ε-caprolactone) (PLLA/HA/PCL) composites via a four-step process, which includes surface etching of the fiber, the deposition of the HA coating onto the PLLA fibers through immersion in simulated body fluid (SBF), PCL coating through a dip-coating process, and hot compression molding. The initial HA-coated PLLA fiber had a homogeneous and continuous coating with a gradient structure. The effects of HA: PCL ratio and molding temperature on flexural mechanical properties were studied and both were shown to be important to mechanical properties. Mechanical results showed that at low molding temperatures and up to an HA: PCL volume ratio of 1, the flexural strain decreased while the flexural modulus and strength increased. At higher mold temperatures with a lower viscosity of the PCL a HA: PCL ratio of 1.6 gave similar properties. The process successfully produced composites with flexural moduli near the lower range of bone. Such composites may have clinical use for load bearing bone fixation.


Related Articles

  • Mechanical properties and in-vivo performance of calcium phosphate cement–chitosan fibre composite. Lian, Q.; Li, D.-C.; He, J.-K.; Wang, Z. // Proceedings of the Institution of Mechanical Engineers -- Part H;Apr2008, Vol. 222 Issue 3, p347 

    Self-hardened calcium phosphate cement (CPC) sets to form hydroxyapatite and possesses excellent osteoconductivity. However, lack of macroporosity and low strength constrain its application in bone tissue engineering. Recent studies have incorporated various fibres into CPC to improve its...

  • Investigation of the Microstructure and the Mechanical Properties of Cu-Ni Composite Produced by Accumulative Roll Bonding and Coating Processes. Shabani, Ali; Toroghinejad, Mohammad // Journal of Materials Engineering & Performance;Dec2015, Vol. 24 Issue 12, p4746 

    In the present study, Cu-1.8 wt.% Ni (nickel coating) composite was produced by the combination of two methods, including accumulative roll bonding (ARB) and electroplating processes. Electroplating process was done on copper strips in order to produce a nickel-particle-reinforced composite....

  • A MODEL FOR THE CALCULATION OF MECHANICAL PROPERTIES OF HYDROXYAPATITE COATINGS ON Ti6AI4V SUBSTRATE USING FINITE ELEMENT METHODS. Pasinli, Ahmet; Culha, Osman; Celik, Erdal; Toparli, Mustafa // Mathematical & Computational Applications;2011 Special Issue, Vol. 16 Issue 1, p136 

    The scope of this study is to find out yield curve on the coating-substrate system of hydroxyapatite (HA) by finite element modeling. With this regard, Hydroxyapatite (HA) coatings were successfully formed on Ti6AI4V substrates by using biomimetic technique. Experimental indentation tests were...

  • Tailoring the Microstructure of Sol-Gel Derived Hydroxyapatite/Zirconia Nanocrystalline Composites. Vasconcelos, HC; Barreto, MC // Nanoscale Research Letters;Jan2011, Vol. 6 Issue 1, p1 

    In this study, we tailor the microstructure of hydroxyapatite/zirconia nanocrystalline composites by optimizing processing parameters, namely, introducing an atmosphere of water vapor during sintering in order to control the thermal stability of hydroxyapatite, and a modified sol-gel process...

  • Microstructure and mechanical properties of Mg-HAP composites. Khanra, Asit; Jung, Hwa; Yu, Seung; Hong, Kug Sun; Shin, Kwang Seon // Bulletin of Materials Science;2010, Vol. 33 Issue 1, p43 

    In the present study, it has been attempted to develop biodegradable Mg-HAP (magnesium-hydroxyapatite) composite materials for bone replacement. At first the HAP powders were prepared by chemical synthesis process and synthesized powders were characterized by X-ray diffraction (XRD) and scanning...

  • Mechanical and thermal properties of biodegradable hydroxyapatite/ poly(sorbitol sebacate malate) composites. Weng Hong Tham; Wahit, Mat Uzir; Kadir, Mohammed Rafiq Abdul; Tuck Whye Wong // Songklanakarin Journal of Science & Technology;Jan/Feb2013, Vol. 35 Issue 1, p57 

    In this project, novel hydroxyapatite (HAp)/poly(sorbitol sebacate malate) (PSSM) composites for potential application in soft tissue engineering were developed. The composites consist of the biodegradable polyester prepared from sorbitol, sebacic acid, malic acid and various amount of HAp (5,...

  • Development of Oxide Dispersion Strengthened MCrAlY Coatings. Bobzin, K.; Schläfer, T.; Richardt, K.; Brühl, M. // Journal of Thermal Spray Technology;Dec2008, Vol. 17 Issue 5/6, p853 

    MCrAlY materials are widely used as bond coats for thermal barrier coatings on turbine blades. The aim of this work is to improve mechanical properties and wear resistance of thermal sprayed NiCoCrAlY-coatings by strengthening the coating with hard phase particles. In order to retain the effect...

  • Investigation of boundary conditions for biomimetic HA deposition on titanium oxide surfaces. Lindgren, M.; Åstrand, M.; Wiklund, U.; Engqvist, H. // Journal of Materials Science: Materials in Medicine;Jul2009, Vol. 20 Issue 7, p1401 

    To improve the clinical outcome of metal implants, i.e. earlier loading and reduction of the incidence of revision surgery, better bone bonding ability is wanted. One method to achieve this is to change the surface chemistry to give a surface that facilitates bone bonding in vivo, i.e. a...

  • Biomimetic apatite formation on Ultra-High Molecular Weight Polyethylene (UHMWPE) using modified biomimetic solution. Aparecida, Anahi H.; Fook, Marcus V. L.; Guastaldi, Antonio C. // Journal of Materials Science: Materials in Medicine;Jun2009, Vol. 20 Issue 6, p1215 

    Modifications were performed on a biomimetic solution (SBF), according to previous knowledge on the behavior of ions present in its composition, in order to obtain apatite coatings onto Ultra-High Molecular Weight Polyethylene (UHMWPE) without having to use polymer pre-treatments that could...


Read the Article

Courtesy of

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics