From crabshell to chitosan-hydroxyapatite composite material via a biomorphic mineralization synthesis method

Haoran Ge; Bingyuan Zhao; Yijian Lai; Xiaobin Hu; Di Zhang; Keao Hu
June 2010
Journal of Materials Science: Materials in Medicine;Jun2010, Vol. 21 Issue 6, p1781
Academic Journal
Hydroxyapatite–polymer composite materials, as biological bone tissue materials, have become an important research direction. In this paper, the calcium carbonate from the crabshells was transformed into hydroxyapatite by a hydrothermal process. According to the method that we called Biomorphic Mineralization synthesis, we obtained a novel kind of hydroxyapatite-chitosan composite materials which reserved the natural perfect structure of the original crabshells. Benefited from its fine micro-structure as the crabshells, this kind of materials held a high value of tensile modulus, which is expected to be promising bone tissue engineering applications.


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