My partner wants a child: A cross-sectional study of the determinants of the desire for children among mutually disclosed sero-discordant couples receiving care in Uganda

Beyeza-Kashesya, Jolly; Ekstrom, Anna Mia; Kaharuza, Frank; Mirembe, Florence; Neema, Stella; Kulane, Asli
January 2010
BMC Public Health;2010, Vol. 10 Issue 1, p247
Academic Journal
Background: The percentages of couples in HIV sero-discordant relationships range from 5 to 31% in the various countries of Africa. Given the importance of procreation and the lack of assisted reproduction to avoid partner transmission, members of these couples are faced with a serious dilemma even after the challenge of disclosing their HIV status to their spouses. Identifying the determinants of the decision to have children among sero-discordant couples will help in setting reproductive intervention priorities in resource-poor countries. Methods: We conducted a survey among 114 mutually disclosed sero-discordant couples (228 individuals) receiving HIV care at four centres in Greater Kampala, between June and December 2007. The data we collected was classified according to whether the man or the woman was HIV-positive. We carried out multivariate logistic regression modelling to determine factors (age, gender, and the influences of relatives and of health workers, ART knowledge, and disclosure) that are independently associated with a desire for children. Results: The majority, 59%, of the participants, desired to have children. The belief that their partner wanted children was a major determinant of the desire to have children, irrespective of the HIV sero-status (adjusted odds ratio 24.0 (95% CI 9.15, 105.4)). Among couples in which the woman was HIV-positive, young age and relatives' expectations for children were significantly associated with increased fertility desire, while among couples in which the man was positive; knowledge of ART effectiveness was associated with increased fertility desire. Availability of information on contraception was associated with decreased fertility desire. Conclusions: The gender of the positive partner affects the factors associated with a desire for children. Interventions targeting sero-discordant couples should explore contraceptive choices, the cultural importance of children, and partner communication.


Related Articles

  • TEHNICI ALTERNATIVE DE DIAGNOSTIC ÅžI MONITORIZARE A INFECÈšIEI HIV. Comănici, Mihaela; Comănici, Adrian; Duiculescu, Dan; Ceauşu, Emanoil; Păun, Ludovic // Romanian Journal of Infectious Diseases;2014, Vol. 17 Issue 1, p22 

    For the diagnosis of HIV infection, current methods can be grouped into two categories: serological methods, identifying the immune response in antibodies, and methods that determine the presence and quantity of virus or viral products. In the category of virus detection tests and viral...

  • Altered immunologic activity in sarcoidosis. Buckley III, C.F.; Nagaya, H.; Sieker, Herbert O.; Buckley, C E 3rd; Sieker, H O // Annals of Internal Medicine;Mar66, Vol. 64 Issue 3, p508 

    Provides information on a study which examined the serologic and cellular functional alterations in the immune response of patients with sarcoidosis. Serum complement activity; Reactivity of cultured lymphocytes; Pathogenesis of sarcoidosis.

  • Characterization of CD8+ T-cell responses in HIV-1-exposed seronegative commercial sex workers from Nairobi, Kenya. Alimonti, Judie B.; Kimani, Joshua; Matu, Lucy; Wachihi, Charles; Kaul, Rupert; Plummrt, Francis A.; Fowke, Krith R. // Immunology & Cell Biology;Oct2006, Vol. 84 Issue 5, p482 

    CD8+ T-lymphocyte responses are crucial to the control of HIV-1; therefore, studying the CD8+ immune response in a naturally resistant population could provide valuable insights into an effective anti-HIV response in healthy uninfected individuals. Approximately 5–10% of the women in the...

  • Factors Associated with Serological Cure and the Serofast State of HIV-Negative Patients with Primary, Secondary, Latent, and Tertiary Syphilis. Tong, Man-Li; Lin, Li-Rong; Liu, Gui-Li; Zhang, Hui-Lin; Zeng, Yan-Li; Zheng, Wei-Hong; Liu, Li-Li; Yang, Tian-Ci // PLoS ONE;Jul2013, Vol. 8 Issue 7, p1 

    Background: Some syphilis patients remain in a serologically active state after the recommended therapy. We currently know too little about the characteristics of this serological response. Methods: We conducted a cohort study using the clinical database from Zhongshan Hospital, Medical College...

  • Alterations in immunoglobulin levels in uninfected children born to HIV infected women. Bunders, Madeleine; Pembrey, Lucy; Kuijpers, Taco; Newell, Marie-Louise // Retrovirology;2008 Supplement 1, Vol. 5, Special section p1 

    Background Immunoglobulin levels are known to be elevated in HIV infected children. However, little is known about the effect of maternal HIV infection and the maternal altered immune system on immunoglobulin levels in uninfected children. As few data are available on immunoglobulins from young...

  • Endogenous Inhibitors of HIV: Potent Anti-HIV Activity of Leukemia Inhibitory Factor. B. K. Patterson; A. Tjernlund; J. Andersson // Current Molecular Medicine;Dec2002, Vol. 2 Issue 8, p713 

    The correlates of protective immunity in HIV-1 infection include the endogenous production of compounds with anti-HIV-1 activity. These compounds can be produced independently of specific humoral or cellular immune responses. A model of compartmental inhibition of HIV-1 infection is the...

  • Born lucky. Cohen, Philip // New Scientist;07/04/98, Vol. 159 Issue 2141, p24 

    Comments on the discovery that some individuals who are exposed to the HIV virus do not become infected. Immune response that does not allow infection; Research by Sharon Stanford of the University of California at San Francisco; Effect of a protein called CD8 that inhibits the replication of...

  • A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques. Chege, G. K.; Chapman, R.; Shephard, E. G.; Williamson, A. // Retrovirology;2012 Supplement, Vol. 9 Issue Suppl 2, p1 

    An abstract of the conference paper "A Prime-Boost Immunization With rBCG Expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C Elicits Immune Responses in Blood and MALT of Rhesus Macaques," by G.K. Chege and colleagues is presented.

  • Protection from Secondary Human Immunodeficiency Virus Type 1 Infection in Chimpanzees Suggests the Importance of Antigenic Boosting and a Possible Role for Cytotoxic T Cells. Balla-Jhagjhoorsingh, S. S.; Mooij, P.; ten Haaft, P. J. F.; Bogers, W. M. J. M.; Teeuwsen, V. J. P.; Koopman, G.; Heeney, J. L. // Journal of Infectious Diseases;7/15/2001, Vol. 184 Issue 2, p136 

    Investigates the possible role of cell-mediated immune responses in protection from secondary HIV type 1 infection. Detection of heterologous infection in vivo; Immune responses that correlate with protection from secondary HIV-1 infection.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics