DGAT1 p.K232A polymorphism in diary and dual purpose Italian cattle breeds

Scotti, Emilio; Fontanesi, Luca; Schiavini, Fausta; La Mattina, Valeria; Bagnato, Alessandro; Russo, Vincenzo
February 2010
Italian Journal of Animal Science;Feb2010, Vol. 9 Issue 1, p79
Academic Journal
The aim of this study was to evaluate the allele frequency distribution at the DGAT1 p.K232A polymorphic site in seven Italian dairy and dual purpose cattle breeds. On the whole, 651 animals belonging to Italian Holstein (116), Italian Brown (105), Italian Simmental (95), Valdostana Red Pied (95), Rendena (62), Reggiana (128) and Modenese (50) breeds were genotyped by PCR-RFLP. Sequencing was carried out to confirm results of the genotyping protocol. The DGAT1 p.232K allele was identified in Italian Holstein (25.4%), Reggiana (17.2%), and with very low frequency in Italian Simmental, Valdostana Red Pied and Rendena (<1%). In Italian Brown and Modenese, this allele was not detected. These results indicated that this polymorphic site can be considered for association studies only in Italian Holstein and Reggiana breeds. Deviation from Hardy- Weinberg equilibrium was observed in the Reggiana breed (P<0.01) in which there was an excess of heterozygous sires and absence of animals with the p.232KK genotype. This result should be further evaluated because the analysed sires represented almost all bulls available for artificial insemination in this breed. Comparison of allele frequencies at the DGAT1 locus with several other Holstein populations showed a wide range of variability, probably due to different selection strategies adopted.


Related Articles

  • What a life - now for peace and quiet. Waugh, John // New Zealand Dairy Exporter;Sep2006, Vol. 82 Issue 2, p46 

    The article offers facts about Collins Royal Hugo, a purebred Holstein Friesian AB bull who has already generated more than $20 million for the dairy industry in New Zealand. He was born on the farm of Neil and Sandra Collins in 1995 and bought by Livestock Improvement as a young calf. His total...

  • Physiology and Endocrinology: Strategies for Appointment Breeding of Beef and Dairy Cattle.  // Poultry Science;2004 Annual Meeting Abstracts, Vol. 83, p255 

    Presents abstracts of research on strategies for appointment breeding of beef and dairy cattle. "MGA and CIDR Based Timed AI Protocols in Postpartum Beef Cows," by D. Kreider, N. Post, R. Rorie, T. Lester and E. French; "Effect of Timing of Insemination and Estrous Synchronization Method on AI...

  • Detection of the Non-SMC Condensin I Complex Subunit G Gene Polymorphism (NCAPG c.1326 T>G) in Different Breeds of Cattle. Trakovická, Anna; Gábor, Michal; Miluchová, Martina; Minarovič, Tomáš; Štastná, Danka // Scientific Papers: Animal Science & Biotechnologies / Lucrari St;Jan2012, Vol. 45 Issue 1, p262 

    The non-synonymous mutation c.1326 T>G in the non-SMC condesin I complex subunit G (NCAPG) gene is asociate with the prenatal growth and carcass weight or growth-associated traits in cattle. The aim of this study was to analyse the population of 50 sires of four breeds (Holstein - 2 bulls,...

  • Accuracy of direct genomic breeding values for nationally evaluated traits in US Limousin and Simmental beef cattle. Saatchi, Mahdi; Schnabel, Robert D.; Rolf, Megan M.; Taylor, Jeremy F.; Garrick, Dorian J. // Genetics Selection Evolution;Dec2012, Vol. 44 Issue 12, p1 

    Background: In national evaluations, direct genomic breeding values can be considered as correlated traits to those for which phenotypes are available for traditional estimation of breeding values. For this purpose, estimates of the accuracy of direct genomic breeding values expressed as genetic...

  • Production, Management and the Environment: Reproduction and Behavior.  // Poultry Science;2004 Annual Meeting Abstracts, Vol. 83, p257 

    Presents abstracts of research on animal production, management and the environment. "Minimum Temperature and Maximum Humidity: Predictors for Conception of Crossbred Holstein Cows in Thailand," by V. Punyapornwithaya et al; "Can Acceptable Pregnancy Rates be Achieved Using Exclusive Timed...

  • The Effect of Holstein X Meat Cattle Breeds Crosses(F1) on Meat Production Increasing in Small Scale Farms Conditions. Papa, L.; Kume, K. // Journal of Tekirdag Agricultural Faculty;2010, Vol. 7 Issue 1, p49 

    About 80 % of Albanian small scale farms farming 1-2 dairy cows. The small agriculture land surface on farm property (1-1,5 ha) is the main limiting factor for cow's number increasing. So the farmer interest is not to increasing the number of cows in their farm but to fattening of calf's born...

  • Early Detection of Non-Pregnant Holstein Cows Subjected to Artificial Insemination by Administration of Intravaginal Progesterone (CIDR). Kaveh, Amirali; Mohammadi, Ali; Nazeri, Mehrdad // Research Journal of Biological Sciences;Aug2011, Vol. 6 Issue 8, p357 

    Artificial insemination breeding programs have long been recommended for dairy producers that raise heifers for herd replacements because of the proven genetic and economic advantages of using Al compared with using natural service bulls for breeding dairy cattle. The aim of this study were to...

  • High merit bulls produce calves the customer wants. Lawrence, Chrissie; Buss, Jessica // Farmers Weekly;8/6/2004, Vol. 141 Issue 6, p32 

    Discusses the practice implemented at the Home Farm, owned by breeder Graham Walker in Cheltenham, England, of choosing high genetic merit beef bulls to increase calf value. Cost of the premium to a superior list issued by Meadow Quality to breeders; Rate of replacement in inseminating cows to...

  • Discovery Project makes its mark. Paterson, David // New Zealand Dairy Exporter;May2009, Vol. 84 Issue 10, p66 

    The article presents information on the Holstein Friesian Discovery Project in Kairanga in New Zealand. This project was organized by the Holstein Friesian Association and LIC. The project is designed to identify elite females of the breed to develop top cow families and potential bull mothers...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics