TITLE

In vitro and in vivo imaging with quantum dots

AUTHOR(S)
Chao Wang; Xue Gao; Xingguang Su
PUB. DATE
June 2010
SOURCE
Analytical & Bioanalytical Chemistry;Jun2010, Vol. 397 Issue 4, p1397
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Quantum dots (QDs), also named semiconductor nanocrystals, have initiated a new realm of bioscience by combining nanomaterials with biology, which will profoundly influence future biological and biomedical research. In this review, we describe the extraordinary optical properties of QDs and developments in methods for their synthesis. We focus on fluorescent imaging with QDs both in vitro and in vivo, and the cytotoxicity of QDs and potential barriers to their use in practical biomedical applications. Finally, we provide insights into improvements aimed at decreasing the cytotoxicity of QDs and the future outlook of QD applications in biomedical fields. [Figure not available: see fulltext.]
ACCESSION #
50870497

 

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