How Does Dabigatran Compare with Warfarin for Secondary Stroke Prevention? Subgroup Analysis of the RE-LY Study

March 2010
MD Conference Express;Mar2010, p14
Academic Journal
The article presents a study which seeks to assess the efficacy of certain doses of dabigatran and warfarin, which are components of anticoagulant therapy, for the prevention of stroke in patients who have already had a stroke or an incidence of transient ischemic attack (TIA). It explores the mechanics of the Randomized Evaluation of Long-term anticoagulant therapy (RE-LY), a random trial applied for patients with nonvalvular atrial fibrillation (AF) who have increased risk factors for stroke or embolism. It also notes that results of the RE-LY proved that 110 mg and 150 mg of dabigatran treatments were much more effective compared to warfarin in preventing hemorrhagic stroke. However, it states that the two drugs bring significant effects for stroke prevention in general.


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