TITLE

Mammographic findings of women recalled for diagnostic work-up in digital versus screen-film mammography in a population-based screening program

AUTHOR(S)
Lipasti, Seppo; Anttila, Ahti; Pamilo, Martti
PUB. DATE
May 2010
SOURCE
Acta Radiologica;May2010, Vol. 51 Issue 5, p491
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Limited information is available concerning differences in the radiological findings of women recalled for diagnostic work-up in digital mammography (DM) versus screen-film mammography (SFM) screening. Purpose: To compare the radiological findings, their positive predictive values (PPVs) for cancer and other process indicators of DM screening performed by computed radiography (CR) technology and SFM screening in a population-based program. Material and Methods: The material consisted of women, 50–59 years of age, who were invited for screening: 30 153 women with DM in 2007–2008 and 32 939 women with SFM in 1999–2000. The attendance rate was 77.7% (23 440) in the DM arm and 83.8% (27 593) in the SFM arm. In the DM arm, 1.71% of those screened (401) and in the SFM arm 1.59% (438) were recalled for further work-up. The images resulting in the recall were classified as: 1) tumor-like mass, 2) parenchymal distortion/asymmetry, 3) calcifications, and 4) combination of mass and calcifications. The distributions of the various radiological findings and their PPVs for cancer were compared in both study groups. The recall rates, cancer detection rates, test specificities, and PPVs of the DM and SFM groups were also compared. Results: Women were recalled for diagnostic work-up most often due to tumor-like mass. It was more common in SFM (1.08% per woman screened) than in DM (0.93%). The second most common finding was parenchymal distortion and asymmetry, more often in DM (0.58%) than in SFM (0.37%). Calcifications were the third most common finding. DM exposed calcifications more often (0.49%) than SFM (0.26%). The PPVs for cancer of the recalls were higher in DM than in SFM in all subgroups of radiological findings. The test specificities were similar (DM 98.9%, SFM 98.8%). Significantly more cancers were detected by DM (cancer detection rate 0.623% per woman screened, n=146) than by SFM (cancer detection rate 0.406% per woman screened, n=112). The PPVs for cancer of all recalls for diagnostic work-up were significantly higher in DM (36%) than in SFM (26%). Conclusion: In DM women were recalled for diagnostic work-up more often for calcifications, parenchymal distortions, and asymmetries than in SFM. In the case of tumor-like masses, more women were recalled in SFM. DM detected more cancers than SFM, and the PPVs for cancer were higher in DM than in SFM in all subgroups of radiological findings.
ACCESSION #
50615504

 

Related Articles

  • OPTIMISATION OF X-RAY EXAMINATIONS IN LITHUANIA: START OF IMPLEMENTATION IN MAMMOGRAPHY. Adlienė, Diana; Adlys, Gediminas; Cerapaite, Reda; Jonaitiene, Egle; Cibulskaite, Inga // Radiation Protection Dosimetry;2005, Vol. 114 Issue 1-3, p399 

    Optimisation of medical X-ray examinations is very important for the enhancement of the reliability of the examination and for the reduction of the radiation dose to patients. Results of investigations of doses to patients during mammography using thermoluminescence dosemeters at different...

  • Factors Affecting Accuracy of Mammography Screening. Sadovsky, Richard // American Family Physician;9/15/2003, Vol. 68 Issue 6, p1198 

    Discusses the study "Individual and Recombined Effects of Age, Breast Density, and Hormone Replacement Therapy Use on the Accuracy of Screening Mammography," by P.A. Carney et al., published on the February 4, 2003 issue of the journal "Annals of Internal Medicine."

  • A HIGH-RESOLUTION VOXEL PHANTOM OF THE BREAST FOR DOSE CALCULATIONS IN MAMMOGRAPHY. Hoeschen, Christoph; Fill, Ute; Zankl, Maria; Panzer, Werner; Regulla, Dieter; Döhring, Wilfried // Radiation Protection Dosimetry;2005, Vol. 114 Issue 1-3, p406 

    Though mammography is one of the most sensitive methods to detect breast cancer, the benefit of the mammography screening programmes is still not clearly proven. One of the reasons is the radiation dose delivered by the examinations. Simulations of the radiation transport based on realistic...

  • An Implementation Intentions Intervention to Increase Uptake of Mammography. Steadman, Liz; Field, Stuart; Rutter, D. R.; Quine, Lyn // Annals of Behavioral Medicine;2006, Vol. 32 Issue 2, p127 

    Background and Purpose: This study tested an implementation intentions intervention to increase uptake in the United Kingdom's National Health Service Breast Screening Programme. The intervention asked women to plan how they would overcome up to 3 previously identified barriers to attending....

  • ORGANISATIONAL ASPECTS OF MAMMOGRAPHY SCREENING IN DIGITAL SETTINGS: FIRST EXPERIENCES OF LUXEMBOURG. Shannoun, F.; Schanck, J. M.; Scharpantgen, A.; Wagnon, M. C.; Ben Daoud, M.; Back, C. // Radiation Protection Dosimetry;2008 Special Issue, Vol. 129 Issue 1-3, p195 

    Luxembourg has been conducting a breast cancer screening programme since 1992, like a large number of other European countries, as early detection and treatment of breast cancer have been proven to reduce mortality. The majority of these screening programmes are based on analogue X-ray...

  • Studies Comparing Screen-Film Mammography and Full-Field Digital Mammography in Breast Cancer Screening: Updated Review. Skaane, P. // Acta Radiologica;Feb2009, Vol. 50 Issue 1, p3 

    Full-field digital mammography (FFDM) has several potential benefits as compared with screen-film mammography (SFM) in mammography screening. Digital technology also opens for implementation of advanced applications, including computer-aided detection (CAD) and tomosynthesis. Phantom studies and...

  • A survey of physicians' attitudes and practices to Screening Mammography in Osogbo & Ibadan, South-West Nigeria. Temitope, Bello O.; Daniel, Adekanle A.; Ademola, Aremu A. // Internet Journal of Radiology;2007, Vol. 6 Issue 2, p2 

    Introduction: Breast cancer is the most common cancer in African women. Screening mammography helps to detect breast cancer before it becomes invasive. The study is aimed at understanding the referral practices of physicians in two cities in South Western Nigeria. Methods: Over a period of four...

  • Screening for Ovarian Cancer: One "Scissor Step" Made. Coleman, Robert L. // OB/GYN Clinical Alert;Jul2009, Vol. 26 Issue 3, p22 

    SUCCESSFUL SCREENING FOR OVARIAN CANCER, THE gynecologic malignancy with the highest case to fatality ratio, has been elusive due to the low prevalence of disease in the general population and the high cost for modalities needed to produce testing specificity acceptable for routine use. The UK...

  • Radiation risk of mammography related to benefit in screening programmes: a favourable balance? Beemsterboer, Petra M. M.; Warmerdam, Peter G.; Boer, Rrob; de Koning, Henry J. // Journal of Medical Screening;Jun1998, Vol. 5 Issue 2, p81 

    Objectives To estimate the number of breast cancer deaths induced by low dose radiation in breast cancer screening programmes compared with numbers prevented. Methods A computer simulation model on the natural history of breast cancer was combined with a model from BEIR-V on induced breast...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics