Early HIV infection: to treat or not to treat?

Stewart, Ann Marie; Weller, Ian; Darbyshire, Janeth
October 1990
BMJ: British Medical Journal (International Edition);10/13/90, Vol. 301 Issue 6756, p825
Academic Journal
Assesses the efficacy of zidovudine in the treatment of early onset of HIV in Great Britain. Risk markers for HIV infections; Progression rate of HIV to AIDS; Development of severe anemia.


Related Articles

  • Combination Therapy for HIV Infection: Getting Closer. Fanci, Anthony S. // Annals of Internal Medicine;1/1/92, Vol. 116 Issue 1, p85 

    Editorial. Comments on issues regarding combination therapy with antiretroviral agents for HIV infection in the U.S. as of January 1992. Observations on research in combination therapy; Views on the use of zidovudine for HIV treatment; Insights on the role of surrogate markers.

  • An antiviral breakthrough. Cohan, Gary R. // Advocate;2/7/95, Issue 674, p43 

    Reports on using AZT with a new drug called 3TC as HIV treatment. Problems with the medications; Benefits and effectiveness of the drug combination.

  • Study shows Retrovir can prevent mother-to-infant HIV transmission.  // New York Amsterdam News;11/12/94, Vol. 85 Issue 46, p14 

    Reports on the preliminary results of a study on the treatment of HIV-infected women and their newborns with Retrovir. Reduction of the risk of maternal-to-fetal transmission of the virus; Food and Drug administration's approval of the drug for the indication; Study protocol.

  • Administration of zidovudine during late pregnancy and delivery to prevent perinatal HIV transmission--Thailand, 1996-1998. Vuthipongse, P.; Bhadrakom, C.; Chaisilwattana, P.; Roongpisuthipong, A.; Chalermchokcharoenkit, A.; Chearskul, S.; Wanprapa, N.; Chokephaibulkit, K.; Tuchinda, M.; Wasi, C.; Chuachoowong, R.; Siriwasin, W.; Chinayon, P.; Asavapiriyanont, S.; Chotpitayasunondh, T.; Waranawat, N.; Sangtaweesin, V.; Horpaopan, S. // JAMA: Journal of the American Medical Association;4/8/98, Vol. 279 Issue 14, p1061 

    Examines the use of zidovudine (ZDV) to prevent perinatal infection with HIV. Testing of drug in the United States and Thailand; Effects of short-term antenatal regimen of ZDV; Methods used in research; Data collected; Estimated HIV transmission risk; Importance of study; Shorter regimen...

  • Medical microbiology.  // Clinical & Investigative Medicine;Aug97 Supplement, Vol. 20, pS56 

    Presents an abstract of the research manuscript `Risk reduction of mother-to-child HIV transmission by antiretroviral therapy in a clinical setting,' by N. Lapointe et al. Zidovudine treatment.

  • Beginning to Make Progress against HIV. Wilfert, Catherine M. // New England Journal of Medicine;11/28/96, Vol. 335 Issue 22, p1678 

    Opinion. Discusses efforts to reduce perinatal human immunodeficiency virus (HIV) infection. Evidence of the preventive efficacy of zidovudine demonstrated by Sperling et al.; How Sperling's work, called Protocol 076, is being implemented in the United States; Details of three studies...

  • Is There A Cure For AIDS?  // Public Health Reports;May/Jun88, Vol. 103 Issue 3, p333 

    The article reveals that presently. there is no cure for AIDS. Medicines such as AZT have prolonged the lives of some patients with AIDS. There is no vaccine to prevent uninfected people from getting AIDS. The article reports that it may take years for an effective, safe vaccine to be found. It...

  • Zidovudine-Induced Macular Edema. Lalonde, Richard G.; Deschenes, Jean G.; Seamone, Christopher // Annals of Internal Medicine;2/15/91, Vol. 114 Issue 4, p297 

    Presents a study that reported the case of a patient with HIV infection and chronic anterior uveitis who had two episodes of serious visual impairment which occurred shortly after the institution of zidovudine therapy. Condition that is common during HIV infection; Reason for the possibility...

  • Response to Lamivudine-Zidovudine plus Abacavir Twice Daily in Antiretroviral-Naive, Incarcerated Patients with HIV Infection Taking Directly Observed Treatment. Kirkland, Larry R.; Fischl, Margaret A.; Tashima, Karen T.; Paar, David; Gensler, Thomas; Graham, Neil M.; Gao, Haitao; Rosenzweig, Jacqueline R. Carranza; McClernon, Daniel R.; Pittman, Ginger; Hessenthaler, Siegrid M.; Hernandez, Jaime E. // Clinical Infectious Diseases;2/15/2002, Vol. 34 Issue 4, p511 

    Prison inmates with human immunodeficiency virus (HIV) infection can be difficult to treat because of the complexity and intrusiveness of many combination antiretroviral therapy regimens. NZTA4007, a 24-week open-label, single-arm clinical trial involving 108 antiretroviral therapy-naive,...

  • New combination therapy for HIV-1 may not be inferior. Volansky, Rob // Infectious Disease News;Nov2008, Vol. 21 Issue 11, p24 

    The article discusses research being done on HIV-1 treatment. It references a study published in "Clinical Infectious Diseases." The study notes that once-daily administration of didanosine, lamivudine and efavirenz demonstrated results that were not inferior to zidovudine, lamivudine and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics