Origin of HIV
Tags: HIV (Viruses); LENTIVIRUSES; AIDS (Disease)
Related Articles
- HIV-1 Gene Therapy at Pre-Integration and Provirus DNA Levels. Nazari, Reza; Joshi, Sadhna // Current Gene Therapy;Feb2009, Vol. 9 Issue 1, p20
AIDS is the result of infection by a lentivirus, HIV-1, which primarily infects CD4+ T cells and macrophages. There is presently no vaccine and none will be available in the foreseeable future. Highly active antiretroviral drug therapy has led to a dramatic reduction of viral load in many...
- New Insights on the Perturbations of T Cell Cycle During HIV Infection. Galati, Domenico; Bocchino, Marialuisa // Current Medicinal Chemistry;2007, Vol. 14 Issue 18, p1920
The role of the Human Immunodeficiency Virus (HIV) in the pathogenesis of the Acquired Immune-Deficiency Syndrome (AIDS) is changed. Direct HIV-mediated killing of CD4+ T cells is not the only mechanism leading to lymphocyte depletion. There is increasing evidence that, during the chronic phases...
- High Rates of Forward Transmission Events after Acute/Early HIV-1 Infection. Brenner, Bluma G.; Roger, Michel; Routy, Jean-Pierre; Moisi, Daniela; Ntemgwa, Michel; Matte, Claudine; Baril, Jean-Guy; Thomas, R�jean; Rouleau, Danielle; Bruneau, Julie; Leblanc, Roger; Legault, Mario; Tremblay, Cecile; Charest, Hugues; Wainberg, Mark A. // Journal of Infectious Diseases;4/1/2007, Vol. 195 Issue 7, p951
Background. A population-based phylogenetic approach was used to characterize human immunodeficiency virus (HIV)-transmission dynamics in Quebec. Methods. HIV-1 pol sequences included primary HIV infections (PHIs; <6 months after seroconversion) from the Quebec PHI cohort (1998-2005; n = 215)...
- Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS. Savarino, Andrea; Pistello, Mauro; D'Ostilio, Daniela; Zabogli, Elisa; Taglia, Fabiana; Mancini, Fabiola; Ferro, Stefania; Matteucci, Donatella; De Luca, Laura; Barreca, Maria Letizia; Ciervo, Alessandra; Chimirri, Alba; Ciccozzi, Massimo; Bendinelli, Mauro // Retrovirology;2007, Vol. 4, p79
Background: Treatment of feline immunodeficiency virus (FIV) infection has been hampered by the absence of a specific combination antiretroviral treatment (ART). Integrase strand transfer inhibitors (INSTIs) are emerging as a promising new drug class for HIV-1 treatment, and we evaluated the...
- Role of Human �-defensins in HIV Infection. Weinberg, A.; Qui�ones-Mateu, M. E.; Lederman, M. M. // Advances in Dental Research;Apr2006, Vol. 19 Issue 1, p42
Mechanisms of resistance to HIV-1 infection in the human oral cavity are incompletely understood. While salivary components have been implicated in protection, there is growing evidence that human beta-defensins (hBDs), originating in oral epithelial cells, may be playing an important role in...
- Differential Mucosal Susceptibility in HIV-1 Transmission and Infection. Moutsopoulos, N. M.; Greenwell-Wild, T.; Wahl, S. M. // Advances in Dental Research;Apr2006, Vol. 19 Issue 1, p52
HIV infection occurs primarily through mucosal surfaces, indicating that protection at mucosal sites may be crucial in prevention and treatment. The host innate and adaptive immune elements provide a level of protection, which differs between mucosal compartments, and appears to be most...
- Prevalence of Antiretroviral Drug Resistance Mutations in Chronically HIV-Infected, Treatment-Naive Patients: Implications for Routine Resistance Screening before Initiation of Antiretroviral Therapy. Novak, Richard M.; Li Chen; MacArthur, Rodger D.; Baxter, John D.; Hullsiek, Kathy Huppler; Peng, Grace; Ying Xiang; Henely, Christopher; Schmetter, Barry; Uy, Jonathan; van den Berg-Wolf, Mary; Kozal, Michael // Clinical Infectious Diseases;2/1/2005, Vol. 40 Issue 3, p468
Background. The prevalence of drug resistance among persons with newly acquired human immunodeficiency virus (HIV) infection is well documented. However, it is unclear to what extent these mutations persist in chronically infected, treatment-naive patients. Methods. Prevalence of and factors...
- Rapid, Multiresistant HIV in New York City Still Worrisome. // Clinical Infectious Diseases;4/15/2005, Vol. 40 Issue 8, preceding p1
The article reports that in a case involving a gay New York City man with rapidly progressing HIV infection resistant to almost all antiretroviral agents, investigators say they have so far been unable to find any host factor that would account for the rapid disease progression or to match the...
- Modulation of cell surface protein expression by infection with HIV-1. Speth, C.; Dierich, M. P. // Leukemia (08876924);Apr1999 Supplement 1, Vol. 13, pS99
The article discusses the modulation of cell surface molecules by HIV-1 with possible effects of modulated expression on HIV-induced pathogenesis. Also, the down-modulation of various complement receptors during HIV infection is reported. It is informed that the enhanced proteolytic cleavage of...
