Bebeklik döneminde ağır kanama bulguları ile getirilen, K vitamini eksikliği ile karışabilen faktör X eksikligiği Üç vaka takdimi

Özdemir, Zeynep Canan; Yıldız, Mahmut; AkÇalı, Mustafa; KoÇ, Ahmet
January 2010
Cocuk Sagligi ve Hastaliklari Dergisi;oca-mar2010, Vol. 53 Issue 1, p36
Academic Journal
Factor X plays an important role in the coagulation cascade, and factor X deficiency can affect both the intrinsic and extrinsic systems. Congenital factor X deficiency is a rare inherited coagulation disorder and is characterized by prolongation of prothrombin time (PT) and partial thromboplastin time (PTT). Therefore, it may be misdiagnosed as vitamin K deficiency in the early infancy period. Bleeding manifestations have been usually mild to moderate. In this article, three cases with severe bleeding symptoms due to severe factor X deficiency are reported. All patients had a mild factor VII deficiency, and two cases had intracranial hemorrhage.


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