TITLE

Immunoassays in microfluidic systems

AUTHOR(S)
Ng, Alphonsus H. C.; Uddayasankar, Uvaraj; Wheeler, Aaron R.
PUB. DATE
June 2010
SOURCE
Analytical & Bioanalytical Chemistry;Jun2010, Vol. 397 Issue 3, p991
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Immunoassays have greatly benefited from miniaturization in microfluidic systems. This review, which summarizes developments in microfluidics-based immunoassays since 2000, includes four sections, focusing on the configurations of immunoassays that have been implemented in microfluidics, the main fluid handling modalities that have been used for microfluidic immunoassays, multiplexed immunoassays in microfluidic platforms, and the emergence of label-free detection techniques. The field of microfluidic immunoassays is continuously improving and has great promise for the future.
ACCESSION #
50377612

 

Related Articles

  • Sequential Push-Pull Pumping Mechanism for Washing and Evacuation of an Immunoassay Reaction Chamber on a Microfluidic CD Platform. Thio, Tzer Hwai Gilbert; Ibrahim, Fatimah; Al-Faqheri, Wisam; Soin, Norhayati; Kahar Bador, Maria; Madou, Marc // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    A centrifugal compact disc (CD) microfluidic platform with reservoirs, micro-channels, and valves can be employed for implementing a complete immunoassay. Detection or biosensor chambers are either coated for immuno-interaction or a biosensor chip is inserted in them. On microfluidic CDs...

  • Surface plasmon resonance biosensor for the detection of VEGFR-1-a protein marker of myelodysplastic syndromes. Pimková, Kristýna; Bocková, Markéta; Hegnerová, Kateřina; Suttnar, Jiří; Čermák, Jaroslav; Homola, Jiří; Dyr, Jan // Analytical & Bioanalytical Chemistry;Feb2012, Vol. 402 Issue 1, p381 

    The surface plasmon resonance (SPR) biosensor system with dispersionless microfluidics for the direct and label-free detection of a soluble vascular endothelial growth factor receptor (sVEGFR-1) is described. The detection approach takes advantage of an affinity interaction between sVEGFR-1 and...

  • Ultra-Portable Smartphone Controlled Integrated Digital Microfluidic System in a 3D-Printed Modular Assembly. Yafia, Mohamed; Ahmadi, Ali; Hoorfar, Mina; Najjaran, Homayoun // Micromachines;2015, Vol. 6 Issue 9, p1289 

    Portable sensors and biomedical devices are influenced by the recent advances in microfluidics technologies, compact fabrication techniques, improved detection limits and enhanced analysis capabilities. This paper reports the development of an integrated ultraportable, low-cost, and modular...

  • Droplet Manipulations in Two Phase Flow Microfluidics. Pit, Arjen M.; Duits, Michèl H. G.; Mugele, Frieder // Micromachines;2015, Vol. 6 Issue 11, p1768 

    Even though droplet microfluidics has been developed since the early 1980s, the number of applications that have resulted in commercial products is still relatively small. This is partly due to an ongoing maturation and integration of existing methods, but possibly also because of the emergence...

  • Microarray Dot Electrodes Utilizing Dielectrophoresis for Cell Characterization. Yafouz, Bashar; Kadri, Nahrizul Adib; Ibrahim, Fatimah // Sensors (14248220);Jul2013, Vol. 13 Issue 7, p9029 

    During the last three decades; dielectrophoresis (DEP) has become a vital tool for cell manipulation and characterization due to its non-invasiveness. It is very useful in the trend towards point-of-care systems. Currently, most efforts are focused on using DEP in biomedical applications, such...

  • Numerical investigation of flow-through immunoassay in a microchannel. Sinha, A; Ganguly, R; Puri, I K. // Journal of Applied Physics;Feb2010, Vol. 107 Issue 3, p034907 

    Immunomagnetic separation (IMS) is a method to isolate biomaterials from a host fluid in which specifically selected antibodies attached to magnetic particles bind with their corresponding antigens on the surface of the target biological entities. A magnet separates these entities from the fluid...

  • Polydimethylsiloxane based Microfluidics Flow PCR Sensor for Bacillus Anthracis using a Disposable Electrode. Ahmed, Minhaz Uddin; Masato Saito; Hossain, M. Mosharraf; Atsushi Hase; Eiichi Tamiya // Indian Journal of Science & Technology;Aug2014, Vol. 7 Issue 8, p1094 

    Conventional Polymerase Chain Reaction (PCR) has been used widely in the clinical diagnostic and environmental monitoring where it still possesses larger volume and thermal mass leading to a slower PCR amplification for ultimate target detection. Microchamber stationary PCR is another...

  • Femtosecond Laser Fabrication of Monolithically Integrated Microfluidic Sensors in Glass. Fei He; Yang Liao; Jintian Lin; Jiangxin Song; Lingling Qiao; Ya Cheng; Koji Sugioka // Sensors (14248220);Oct2014, Vol. 14 Issue 10, p19402 

    Femtosecond lasers have revolutionized the processing of materials, since their ultrashort pulse width and extremely high peak intensity allows high-quality micro- and nanofabrication of three-dimensional (3D) structures. This unique capability opens up a new route for fabrication of...

  • Development of a Digital Micropump with Controlled Flow Rate for Microfluidic Platforms. Paknahad, Mohammad; Nejad, Hojatollah Rezaei; Hoorfar, Mina // Sensors & Transducers (1726-5479);Dec2014, Vol. 183 Issue 12, p84 

    This paper presents a novel device for pumping a column of liquid in a microchannel integrated on a digital microfluidic (DMF) platform. The electrowetting on dielectric (EWOD) method is used to frequently actuate a droplet (referred to as the piston droplet) on an array of electrodes. A column...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics