The relationship between coronary slow flow phenomenon and coronary calcium score

Oz, Ozgur; Bayram, Nihal Akar; Durmaz, Tahir; Keles, Telat; Akcay, Murat; Bozkurt, Engin
March 2010
Perfusion;Mar2010, Vol. 25 Issue 2, p97
Academic Journal
Aim: Coronary slow flow phenomenon (CSFP) is an angiographic finding characterized by delayed distal vessel opacification without any significant epicardial coronary artery disease. Several studies have suggested that CSFP might be a form of atherosclerosis. The present study was aimed to investigate the relationship between CSFP and coronary artery calcification, which is one of the clear-cut indicators of coronary atherosclerotic plaque, by using computerized tomography. Method: Fifty-five patients were included in the study. The coronary arteries of all patients were shown by angiography to be normal. Coronary slow flow (CSF) patterns were evaluated by the thrombolysis in myocardial infarction frame count (TFC) method. Patients with normal coronary arteries and CSF were allocated into the CSF group, and patients with normal coronary arteries and normal coronary flow were allocated into the control group. Coronary artery calcium (CAC) score was measured in 28 patients with CSF and in 27 controls by 64-slice computerized tomography. Results: The CSF and control groups were similar with respect to age, gender, smoking status, presence of hypertension and diabetes mellitus, cholesterol profiles, and Framingham risk scores (p>0.05). The CSF and control groups were not significantly different with respect to CAC score (p>0.05). Sub-group analysis of cardiac risk factors in patients with or without coronary artery calcification revealed that advanced age and low high density lipoprotein (HDL) levels were significantly associated with coronary artery calcification. There wasn't any relationship between coronary slow flow and cardiac risk factors or coronary calcium scores. Conclusion: In the present study, no association was found between the CSFP and calcified atherosclerosis. Additionally, it was demonstrated that, among the cardiac risk factors, advanced age and low HDL levels were associated with coronary artery calcification.


Related Articles

  • COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study. Huuskonen, Kati H.; Kunnas, Tarja A.; Tanner, Minna M.; Mikkelsson, Jussi; Ilveskoski, Erkki; Karhunen, Pekka J.; Nikkari, Seppo T. // Mediators of Inflammation;2008, Vol. 2008, Special section p1 

    Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the -765G → C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis...

  • Reduced In-Hospital Mortality Following Intracoronary Streptokinase Treatment of Acute Myocardial Infarction. Salem, Bakr I.; Gowda, Siddhesh; Haikal, Maged // Vascular Surgery;May/Jun1987, Vol. 21 Issue 3, p215 

    Reduced short-term mortality following thrombolytic treatment of acute myocardial infarction has been reported by earlier studies. This study was performed to compare data from our institution with such results. From January, 1984, through January, 1986, a total of 628 consecutive patients were...

  • Fluorouracil.  // Reactions Weekly;3/13/2004, Issue 992, p8 

    Discusses research being done on the side effects of fluorounacil in a patient with advanced cervical adenocarcinoma. Reference to a study by J. D. Abbott and colleagues, published in the November/ December 2003 issue of the "Angiology"; Occurrence of myocardial infarction and spontaneous...

  • IMAGES IN CARDIOLOGY: Left ventricular pseudoaneurysm following myocardial infarction. Ropers, D.; Achenbach, S.; Pfeiffer, S. // Heart;May2004, Vol. 90 Issue 5, p555 

    An asymptomatic 61 year old man with a history of coronary artery disease, including coronary artery bypass surgery, presented for routine examination after a lateral myocardial infarction treated by thrombolysis five months previously. Physical examination was unremarkable. Echocardiography...

  • Morphological abnormalities revealed after successful intra-arterial thrombolysis of infra-inguinal native arteries and bypasses. Sandbaek, G.; Staxrud, L.E.; Rosen, L.; Kolmannskog, F.; Rosén, L // Acta Radiologica;Jan1999, Vol. 40 Issue 1, p23 

    Purpose: To characterise morphological abnormalities depicted after successful intra-arterial thrombolysis; to determine whether these differed in infra-inguinal native arteries and bypasses; and to evaluate whether balloon angioplasty was an appropriate treatment of stenoses in the...

  • Timing of coronary artery bypass grafting after acute... Wasvary, Harry; Shannon, Francis // American Surgeon;Aug1997, Vol. 63 Issue 8, p710 

    Presents a study on the appropriate timing for coronary artery bypass grafting (CABG) after acute myocardial infarction (AMI). Patients and methods used in the study; Myocardial infraction/coronary artery disease characteristics; Results of the study; Conclusion.

  • Percutaneous Coronary Intervention.  // Current Medical Literature: Cardiology;2010, Vol. 29 Issue 2, p52 

    The article discusses studies on coronary disease intervention. It cites the Norwegian Study on District Treatment of ST-segment elevation myocardial infarction (STEMI) on percutaneous coronary intervention for treating STEMI patients with thrombolysis in rural areas. It mentions a report on the...

  • Hepatitis C Virus Infection and Coronary Artery Disease Risk: A Systematic Review of the Literature. Wong, Robert; Kanwal, Fasiha; Younossi, Zobair; Ahmed, Aijaz // Digestive Diseases & Sciences;Jul2014, Vol. 59 Issue 7, p1586 

    Background and Aims: While hepatitis C virus (HCV) infection has been implicated in increasing the risk of coronary artery disease (CAD), conflicting reports exist regarding this association. We performed a systematic review to further investigate this association. Methods: We conducted a PubMed...

  • Association Between Endoscopic vs Open Vein-Graft Harvesting and Mortality, Wound Complications, and Cardiovascular Events in Patients Undergoing CABG Surgery. Williams, Judson B.; Peterson, Eric D.; Brennan, J. Matthew; Sedrakyan, Art; Tavris, Dale; Alexander, John H.; Lopes, Renato D.; Dokholyan, Rachel S.; Yue Zhao; O'Brien, Sean M.; Michler, Robert E.; Thourani, Vinod H.; Edwards, Fred H.; Duggirala, Hesha; Gross, Thomas; Marinac-Dabic, Danica; Smith, Peter K. // JAMA: Journal of the American Medical Association;8/1/2012, Vol. 308 Issue 5, p475 

    The article provides information on a research study which examined 3000 patients undergoing coronary artery bypass graft (CABG) surgery enrolled in the PREVENT IV trial. The study compared the long-term outcomes of endoscopy against open vein-graft harvesting for Medicare patients undergoing...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics