TITLE

Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis

AUTHOR(S)
Nalini, S.; Lakshmi, R.; Devika, K.; Ravikumar, D.; Ramachandran, R.
PUB. DATE
April 2010
SOURCE
Indian Journal of Medical Microbiology;Apr2010, Vol. 28 Issue 2, p162
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A low-cost method of detecting multi-drug resistant Mycobacterium tuberculosis (MDR-TB) with the possibility of quick adoption in a resource limited setting is urgently required. We conducted a study combining isoniazid and rifampicin in a single LJ medium, to detect MDR-TB strains. Combined and individual drug media showed 100% concordance for the detection of MDR-TB and susceptible strains by proportion method. Considering the results, combined isoniazid and rifampicin containing medium could be considered for use in settings where the sole detection of MDR-TB strains is justified.
ACCESSION #
50137889

 

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