TITLE

Infection with hepatitis C virus genotype 3 - Experience of a tertiary health care centre in south India

AUTHOR(S)
David, J.; Rajasekar, A.; Daniel, H. D. D.; Ngui, S. L.; Ramakrishna, B.; Zachariah, U. G.; Eapen, C. E.; Abraham, P.
PUB. DATE
April 2010
SOURCE
Indian Journal of Medical Microbiology;Apr2010, Vol. 28 Issue 2, p155
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
To analyse the response rate and the predictive values of virological, biochemical and histological factors on HCV antiviral therapy in HCV genotype 3 infected patients, we retrospectively studied 21 HCV genotype 3 infected patients, who underwent HCV antiviral therapy. Low (57%) sustained viral response (SVR) rate and significant association of SVR with normalization of alanine transaminase (ALT) levels were observed in our study. Absence of early viral response (EVR) showed high (80%) predictive value on SVR. Absence of EVR and normalisation of the ALT levels can predict the outcome of HCV antiviral therapy.
ACCESSION #
50137887

 

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