TITLE

Correlations between genotyping and antibiograms of clinical isolates of Pseudomonas aeruginosa from three different south Indian hospitals

AUTHOR(S)
Prashanth, K.; Singh, S. K.; Kanungo, R.; Sharma, S.; Shashikala, P.; Joshi, S.; Jayachandran, S.
PUB. DATE
April 2010
SOURCE
Indian Journal of Medical Microbiology;Apr2010, Vol. 28 Issue 2, p130
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: To compare the molecular relationships and antibiograms of nosocomial isolates of Pseudomonas aeruginosa obtained from three different genres of hospitals located in Southern India, two located at Hyderabad (one private hospital and an ophthalmic hospital) and one in Puducherry (tertiary care teaching hospital). Each of these hospitals, which follow different infection control strategies and various problems associated with it, were investigated. Materials and Methods: Antibiograms generated by disk diffusion susceptibility testing for clinically relevant antibiotics and genotyping through fluorescent amplified fragment length polymorphism analysis (fAFLP) were the tools used in the study. Results: Molecular genotyping revealed a heterogeneous group of unrelated molecular clusters of P. aeruginosa strains having higher resistance that are apparently being endemic throughout the tertiary care teaching hospital. In eye care hospital, only a few distinct strains of P. aeruginosa predominating the study period were shown to be responsible for outbreaks. The third private hospital witnessed a group of resistant and persistent strains that might have clonally originated from a diverse collection of strains. Conclusions: The divergent kind of strains in our study suggests that there may be a direct link between the infection control practices followed in each hospital and kind of strains isolated in that particular setup. The study also emphasizes the need for maintaining infection control practices in hospitals with superior standards, failure of which might result in thriving of persistent P. aeruginosa clones in the hospitals.
ACCESSION #
50137882

 

Related Articles

  • Multiple genotypic changes in hypersusceptible strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients do not always correlate with the phenotype. Wolter, Daniel J.; Black, Jennifer A.; Lister, Philip D.; Hanson, Nancy D. // Journal of Antimicrobial Chemotherapy (JAC);Aug2009, Vol. 64 Issue 2, p294 

    Objectives Although Pseudomonas aeruginosa from cystic fibrosis patients are well known for their antibiotic resistance, isolates that are highly susceptible to multiple drug classes have also been encountered. In this study, hypersusceptible P. aeruginosa isolates were analysed for changes in...

  • Characterization of Pseudomonas aeruginosa Strains Isolated from Burned Patients Hospitalized in a Major Burn Center in Tehran, Iran. Ranjbar, Reza; Owlia, Parviz; Saderi, Horie; Mansouri, Sadegh; Jonaidi-Jafari, Nematollah; Izadi, Morteza; Farshad, Shohreh; Arjomandzadegan, Mohammad // Acta Medica Iranica;2011, Vol. 49 Issue 10, p675 

    Abstract- Pseudomonas aeruginosa is an important life-threatening nosocomial pathogen and plays a prominent role in serious infections in burned patients. The current study was undertaken to characterize P. aeruginosa strains isolated from burned patients in Tehran, Iran. The study was conducted...

  • The Prevalence and Resistance Patterns of Pseudomonas aeruginosa in Intensive Care Units in a University Hospital. Savaş, Lütfü; Duran, Nizami; Savaş, Nazan; Önlen, Yusuf; Ocak, Sabahattýn // Turkish Journal of Medical Sciences;2005, Vol. 35 Issue 5, p317 

    The intensive care units (ICUs) are burdened with a high frequency of nosocomial infections often caused by multiresistant nosocomial pathogens. Pseudomonas aeruginosa has emerged as one of the most problematic Gram-negative pathogens. The objective of this study was to identify frequency of...

  • Resistencia antimicrobiana en aislados clínicos de Pseudomonas aeruginosa. Casal, María del Mar; Causse, Manuel; Rodríguez-López, Fernando; Casal, Manuel // Revista Española de Quimioterapia;mar2012, Vol. 25 Issue 1, p37 

    Pseudomonas aeruginosa is an opportunistic microorganism that is frequently the cause of nosocomial infections. Multiple mechanisms are involved in its natural and acquired resistance to many of the antimicrobial agents commonly used in clinical practice. We performed an antibiotic resistance...

  • Dissemination of IMP-6-producing Pseudomonas aeruginosa ST244 in multiple cities in China. Chen, Y.; Sun, M.; Wang, M.; Lu, Y.; Yan, Z. // European Journal of Clinical Microbiology & Infectious Diseases;Jul2014, Vol. 33 Issue 7, p1181 

    Pseudomonas aeruginosa is an important opportunistic pathogen responsible for nosocomial infections and is currently reported to be a worldwide nosocomial menace. The aim of this study was to investigate the epidemiological traits and the distribution of metallo-β-lactamases (MBLs)-producing...

  • Microbiological Surveillance of the Surgical Intensive Care Unit in Zagreb -- A Pivot for Guideline-Based Therapy of Severe Sepsis. Mihaljević, Ljiljana; Bedenić, Branka; Mihaljević, Slobodan; Majerović, Mate; Petrović, Pavo; Vasilj, Ivan // Collegium Antropologicum;Dec2007, Vol. 31 Issue 4, p1093 

    The aim of this retrospective study was to create guidelines for therapy of severe sepsis in surgical intensive care unit (ICU) for unknown causative agent based on antimicrobial susceptibility of causative bacteria. Seventy-four patients with severe sepsis from surgical ICU in 2003.-2005. were...

  • Do wheelchairs spread pathogenic bacteria within hospital walls? Peretz, Avi; Koiefman, Anna; Dinisman, Eleonora; Brodsky, Diana; Labay, Kozitta // World Journal of Microbiology & Biotechnology;Feb2014, Vol. 30 Issue 2, p385 

    Transmission of nosocomial pathogens has been linked to transient colonization of health care workers, medical devices and other constituents of patients' environment. In this paper we present our findings concerning the presence of pathogenic bacteria on wheelchairs, and the possibility that...

  • Antimicrobial susceptibility and minimal inhibitory concentration of Pseudomonas aeruginosa isolated from septic ocular surface disease in different animal species. Leigue, L.; Montiani-Ferreira, F.; Moore, B. A. // Open Veterinary Journal;2016, Vol. 6 Issue 3, p215 

    The purpose of this study was to evaluate the antibiotic susceptibility profile of Pseudomonas aeruginosa isolated from different animal species with septic ocular surface disease. Sixteen strains of P. aeruginosa were isolated from different species of animals (dog, cat, horse, penguin and...

  • The peculiarities of burn wound contamination. Samartsev, V. A.; Encheva, Y. A.; Kuznetsova, M. V.; Karpunina, T. I. // Surgery News / Novosti Hirurgii;2014, Vol. 22 Issue 2, p199 

    Objectives. To reveal the peculiarities of burn wound contamination taking into account antibiotic sensitivity and genotypic characteristics of dominant pathogens. Methods. The medical records from the burn unit of Perm multi-type hospital have been analyzed for the period 2011-2012 yrs....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics