TITLE

Perspektywy leaniczych zastosowań kannabinoidów w chorobach przewodu pokarmowego

AUTHOR(S)
Rutkowska, Maria; Słupski, Wojciech; Sozański, Tomasz; Szeląg, Adam
PUB. DATE
November 2009
SOURCE
Gastroenterologia Polska / Gastroenterology;2009, Vol. 16 Issue 6, p451
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The endogenous cannabinoid system and its role in the physiology and pathophysiology of the digestive system is presented. The potential use of agonists and antagonists of cannabinoid receptors in such disorders as nausea and vomiting, peptic ulcer disease, gastroesophageal reflux disease, irritable bowel syndrome, inflammation, and paralytic ileus are discussed. Differences in the pharmacological action of these substances in animals and humans as well as the observed side effects are also considered. Pharmacological modulation of the endogenous cannabinoid system could provide a new therapeutic target for the treatment of a number of gastrointestinal diseases.
ACCESSION #
49814345

 

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