Perspektywy leaniczych zastosowań kannabinoidów w chorobach przewodu pokarmowego

Rutkowska, Maria; Słupski, Wojciech; Sozański, Tomasz; Szeląg, Adam
November 2009
Gastroenterologia Polska / Gastroenterology;2009, Vol. 16 Issue 6, p451
Academic Journal
The endogenous cannabinoid system and its role in the physiology and pathophysiology of the digestive system is presented. The potential use of agonists and antagonists of cannabinoid receptors in such disorders as nausea and vomiting, peptic ulcer disease, gastroesophageal reflux disease, irritable bowel syndrome, inflammation, and paralytic ileus are discussed. Differences in the pharmacological action of these substances in animals and humans as well as the observed side effects are also considered. Pharmacological modulation of the endogenous cannabinoid system could provide a new therapeutic target for the treatment of a number of gastrointestinal diseases.


Related Articles

  • The palliative care approach to nausea and vomiting. Auty, Simon // GP: General Practitioner;6/2/2006, p26 

    The article presents information related to the palliative care approach to nausea and vomiting. Nausea is the unpleasant sensation that one feels when they need to vomit. Vomiting is the reflex action of propelling the contents of the stomach out through the mouth. Nausea and vomiting can...

  • Cannabinoids in the Treatment of Symptoms in Cancer and AIDS, 2nd Edition #93. Wilner, L. Scott; Arnold, Robert M. // Journal of Palliative Medicine;Apr2011, Vol. 14 Issue 4, p509 

    The article focuses on the treatment of symptoms of cancer and AIDS using cannabinoids. It says that cannabinoids are the biologically active component found in the cannabis sativa, an Indian hemp plant, which affects the CB2 receptor in the central nervous system (CNS) and CB2 receptor of...

  • IT'S A PAIN.  // American Herb Association Quarterly Newsletter;Fal2011, Vol. 26 Issue 4, pp12 

    The article discusses research being done on cannabinoid compounds from cannabis which references several placebo studies.

  • Cannabinoids for Medical Use: A Systematic Review and Meta-analysis. Whiting, Penny F.; Wolff, Robert F.; Deshpande, Sohan; Di Nisio, Marcello; Duffy, Steven; Hernandez, Adrian V.; Keurentjes, Christiaan; Lang, Shona; Misso, Kate; Ryder, Steve; Schmidlkofer, Simone; Westwood, Marie; Kleijnen, Jos // JAMA: Journal of the American Medical Association;6/23/2015, Vol. 313 Issue 24, p2456 

    IMPORTANCE Cannabis and cannabinoid drugs are widely used to treat disease or alleviate symptoms, but their efficacy for specific indications is not clear. OBJECTIVE To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. DATA SOURCES Twenty-eight databases from...

  • New Generation Agents for the Prevention of Chemotherapy-Induced Nausea and Vomiting. Sankhala, Kamalesh K.; Karnad, Anand B. // European Journal of Clinical & Medical Oncology;2011, Vol. 3 Issue 3, p10 

    Chemotherapy-induced nausea and vomiting (CINV) is associated with a significant decline in quality of life in cancer patients. The morbidity due to CINV depends on the chemotherapeutic agent, the number of repeated cycles of treatment, and patient characteristics. Discontinuation of...

  • Stability of an extemporaneous oral liquid aprepitant formulation. Karen Lingertat-Walsh // Supportive Care in Cancer;Jun2009, Vol. 17 Issue 6, p701 

    Abstract Goals of work  Aprepitant is currently recommended for the prevention of acute antineoplastic-induced nausea and vomiting in adults receiving highly emetogenic therapy. The lack of an oral liquid dosage form is one barrier to its use in children. The purpose of this study was to...

  • Cannabinoids act backwards. Christie, MacDonald J.; Vaughan, Christopher W. // Nature;3/29/2001, Vol. 410 Issue 6828, p527 

    Discusses the use of the cannabis plant to treat ailments. Cannabinoid receptors on nerve cells; Side effects of the therapeutic use of the plant; Reference to a study in this issue by Wilson and Nicoll; Effect of the plant on the nervous system; Idea to use drugs that control signalling by...

  • Do current antiemetic practices result in positive patient outcomes? Results of a new study. Wender, Ronald H. // American Journal of Health-System Pharmacy;1/2/2009, Vol. 66 Issue S1, pS3 

    Purpose. The problem of perioperative nausea and vomiting (including postoperative and postdischarge nausea and vomiting [PONV/PDNV]) among people undergoing general anesthesia is discussed. Summary. Nausea and vomiting are not limited to the postanesthesia care unit (PACU) or the hospital, but...

  • Pathophysiology and pharmacotherapy of nausea and emesis. Davis, W. Marvin // Drug Topics;10/18/99, Vol. 143 Issue 20, p96 

    Presents information on a study which reviewed the neural mechanism of nausea and vomiting, conditions that evoke response and approaches for their management. Neural basis of nausea and vomiting (NV); Pathophysiology of NV; Pharmacotherapy of NV; Conclusions.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics