In-vitro antioxidant activities of methanolic extract of tuberous root of Ipomoea digitata (Linn.)

Vasagam, G. Alagumani; Muthu, A. Kottai; kumar, D. Satheesh; Manavalan, R.
March 2010
Journal of Pharmacy Research;Mar2010, Vol. 3 Issue 3, p639
Academic Journal
In vitro antioxidant activities of methanol extract of tuberous root of Ipomoea digitata (Linn.) was investigated. The free radical scavenging activity to evaluate by DPPH (2, 2-diphenyl -1- picryl hydrazyl) method, superoxide anion scavenging and iron chelating activity. DPPH radical scavenging activity of Methanolic extract and reference standard Rutin IC50 values was found to be 240 mg/ml and 480 mg/ml, superoxide anion scavenging activity of methanolic extract and reference standard Quercetin IC50 values was found to be 99 mg/ml and 60 mg/ ml and iron chelating activity of methanolic extract and reference standard EDTA IC50 values was found to be 440 mg/ml and 65 mg/ml respectively. The above result of possess good an antioxidant activity when compare to the above all standard.


Related Articles

  • Nanoparticulated Quercetin in Combating Age Related Cerebral Oxidative Injury. Das, Sanchari; Mandal, Ardhendu K.; Ghosh, Aparajita; Panda, Subhamay; Das, Nirmalendu; Sarkar, Sibani // Current Aging Science;Dec2008, Vol. 1 Issue 3, p169 

    Reactive oxygen species e.g. O2?-, H2O2 and �H generated by the induction of oxidative stress exert a potential threat on the activity of endogenous antioxidant enzymes and substantially influence the aging process and age-dependant neuropathology. Chemical antioxidant is almost ineffective...

  • In vitro antioxidant activity of Holarrhena antidysenterica Wall. methanolic leaf extract. Ganapathy, P. S. Sujan; Ramachandra, Y. L.; Rai, S. Padmalatha // Journal of Basic & Clinical Pharmacy;Sep-Nov2011, Vol. 2 Issue 4, p175 

    Antioxidative potential of methanolic leaf extract of Holarrhena antidysenterica was evaluated using hydroxyl radical, superoxide anion scavenging and reducing power assays. The antioxidant activity of the methanol extract increased in a concentration-dependent manner. The extract showed...

  • Morphology and oxidative physiology of boron-deficient mulberry plants. TEWARI, RAJESH KUMAR; KUMAR, PRAVEEN; SHARMA, PARMA NAND // Tree Physiology;Jan2010, Vol. 30 Issue 1, p68 

    The aim of the study was to induce B deficiency symptoms and to relate the generation of reactive oxygen species (ROS) and altered cellular redox environment with the effects of B deficiency in mulberry (Morus alba L.) cv. Kanva-2 plants. Study was undertaken on antioxidant responses,...

  • Growth and Physiological Characteristics of E. coli in Response to the Exposure of Sound Field. Shao-Bin Gu; Bin Yang; Ying Wu; Shi-Chang Li; Wen Liu; Xiao-Fei Duan; Meng-Wei Li // Pakistan Journal of Biological Sciences;2013, Vol. 16 Issue 18, p969 

    It is undeniable that environmental sonic vibration can affect our emotions and mood, but so far the study of physical stimuli provoked by audible wave on single cells has been rarely concerned. To investigate the response of E. coli to audible wave exposure, the growth status and alterations in...

  • Effect of Zingiber officinale on liver oxidative status and biochemical parameters in rats exposed to paraquat. Almasi, Hossein; Habibian, Reza; Kamali, Midia // Comparative Clinical Pathology;Nov2013, Vol. 22 Issue 6, p1165 

    Oxidative stress caused by reactive oxygen species is one of the major pathogenesis of important diseases of animals and human. Paraquat is widely used as herbicide. The toxicity of paraquat is through induction of oxidative processes in biological systems. Biochemically, this herbicide...

  • Obesity and oxidative stress: a direct link to preeclampsia? Zavalza-Gómez, Ana // Archives of Gynecology & Obstetrics;Mar2011, Vol. 283 Issue 3, p415 

    Overweight is associated with alterations in lipid concentrations and an activation of inflammatory markers and both of these metabolic abnormalities are characteristic of preeclamptic pregnancies before the onset of clinically evident disease. Reactive oxygen species, particularly superoxide...

  • Oxidative stress - call for papers. Ryan, Michael J. // Clinical Science;Jan2017, Vol. 131 Issue 2, p139 

    No abstract available.

  • Role of Reactive Oxygen Species and Antioxidants in Atopic Dermatitis. SIVARANJANI, N.; VENKATA RAO, S.; RAJEEV, G. // Journal of Clinical & Diagnostic Research;Dec2013, Vol. 7 Issue 12, p2683 

    Background: In humans, oxidative stress is involved in many diseases such as atherosclerosis, Parkinson's disease, heart failure, myocardial infarction, Alzheimer's disease, Fragile X syndrome and chronic fatigue syndrome. Atopic dermatitis (AD), also known as atopic eczema, is a non-contagious,...

  • Oxidative stress in the placenta. Myatt, Leslie; Cui, Xiaolan // Histochemistry & Cell Biology;Oct2004, Vol. 122 Issue 4, p369 

    Pregnancy is a state of oxidative stress arising from increased placental mitochondrial activity and production of reactive oxygen species (ROS), mainly superoxide anion. The placenta also produces other ROS including nitric oxide, carbon monoxide, and peroxynitrite which have pronounced effects...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics