Thiazolidinediones and Risk of Heart Failure

April 2010
Internal Medicine Alert;4/15/2010 Pharmacolo, p1
The article offers updates related to pharmacology in the U.S., including the review conducted by the Food and Drug Administration (FDA) on the safety of thiazolidinediones (TZDs), an article "Annals of Internal Medicine" which stated that metformin has a fishy smell that causes nausea, and the approval of pneumococcal vaccine for infants and children.


Related Articles

  • A Decade of Data Mining and Still Counting. Hauben, Manfred; Norén, G. Niklas // Drug Safety;2010, Vol. 33 Issue 7, p527 

    The article discusses various reports on pharmacovigilance which are published within the issue including one by A. M. Hochberg and colleagues on three signal-detection algorithms, one by Y. Alvarez and colleagues on the validation of statistical signal detection procedures in Eudra Vigilance...

  • Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial. Pomat, William S.; van den Biggelaar, Anita H. J.; Phuanukoonnon, Suparat; Francis, Jacinta; Jacoby, Peter; Siba, Peter M.; Alpers, Michael P.; Reeder, John C.; Holt, Patrick G.; Richmond, Peter C.; Lehmann, Deborah // PLoS ONE;Feb2013, Vol. 8 Issue 2, p1 

    Background: Approximately 826,000 children, mostly young infants, die annually from invasive pneumococcal disease. A 6-10-14-week schedule of pneumococcal conjugate vaccine (PCV) is efficacious but neonatal PCV may provide earlier protection and better coverage. We conducted an open randomized...

  • Statistical techniques for signal generation: the Australian experience. Purcell, P.; Barty, S.; Purcell, Patrick; Barty, Simon // Drug Safety;Apr2002, Vol. 25 Issue 6, p415 

    National voluntary reporting systems generate large volumes of clinical data pertinent to drug safety. Currently descriptive statistical techniques are used to assist in the detection of drug safety 'signals'. Australian data have been coded according to guidelines formulated almost 30 years ago...

  • Signal selection and follow-up in pharmacovigilance. Meyboom, R.H.B.; Lindquist, M.; Egberts, A.C.G.; Edwards, I.R.; Meyboom, Ronald H B; Lindquist, Marie; Egberts, Antoine C G; Edwards, I Ralph // Drug Safety;Apr2002, Vol. 25 Issue 6, p459 

    The detection of unknown and unexpected connections between drug exposure and adverse events is one of the major challenges of pharmacovigilance. For the identification of possible connections in large databases, automated statistical systems have been introduced with promising results. From the...

  • Pharmacoepidemiologic research in Australia: challenges and opportunities for monitoring patients with rheumatic diseases. Lu, Christine Y. // Clinical Rheumatology;Apr2009, Vol. 28 Issue 4, p371 

    The topic of drug safety has received great attention in recent years. Pharmacoepidemiology is the study of the use and effects of medicines in large populations using epidemiological methods. Pharmacoepidemiologic research can fill the knowledge gaps due to the limitations of existing...

  • Pneumococcal colonization in older adults. Esposito, Susanna; Mari, Daniela; Bergamaschini, Luigi; Orenti, Annalisa; Terranova, Leonardo; Ruggiero, Luca; Ierardi, Valentina; Gambino, Monia; Della Croce, Francesco; Principi, Nicola // Immunity & Ageing;1/12/2016, Vol. 13, p1 

    Background: Little is known about pneumococcal carrier states in older adults. The main aim of this study was to evaluate pneumococcal colonization patterns among older adults in two centres in Milan, Italy, before the widespread use of the 13-valent pneumococcal vaccine (PCV13) in this age...

  • Important lessons from the confusion with COX-2 inhibitors.  // Reactions Weekly;1/15/2005, Issue 1034, p4 

    Discusses research being done on the cardiovascular safety of COX-2 inhibitors. Reference to a study by Eric J. Topol published in the January 19 2005 issue of the "Journal of the American Medical Association"; Suspension of the Alzheimer's Disease Anti-Inflammatory Prevention Trial;...

  • Individual case safety reports in children in commonly used drug groups -- signal detection. Brunlöf, Gertrud; Tukukino, Carina; Wallerstedt, Susanna M. // BMC Clinical Pharmacology;2008, Vol. 8, Special section p1 

    Background: Due to few paediatric drug safety studies, knowledge on risks of drug treatment in children is limited. The knowledge needs to be increased to make proper risk-benefit analyses possible when treating paediatric patients with drugs. The aim of the present study was to investigate drug...

  • O Sistema Portugu�s de Farmacovigil�ncia. HERDEIRO, Maria Teresa; FERREIRA, M�nica; RIBEIRO-VAZ, In�s; POL�NIA, Jorge JUNQUEIRA; COSTA-PEREIRA, Altamiro // Acta Medica Portuguesa;Jul/Aug2012, Vol. 25 Issue 4, p241 

    In Portugal, the National Pharmacovigilance System (NPS) was created in 1992, completing during this year 20 years of existence. Having been established in a centralized manner, it soon became aware that its geographic decentralization would bring advantages in terms of proximity of the System...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics