Rationalisation of regimens of treatment of kala-azar with sodium stibogluconate in India: a randomised study

Thakur, C.P.; Kumar, M.; Kumar, P.; Mishra, B.N.; Pandey, A.K.
June 1988
British Medical Journal (Clinical Research Edition);6/4/1988, Vol. 296 Issue 6636, p1557
Academic Journal
Evaluates the efficacy and safety of regimens for kala-azar with sodium stibogluconate treatment of patients in India. Number of patients with temperature returning to normal at the end of regimen treatment; Implication on the logistics regression of cured patients; Conclusion on sodium stibogluconate administration.


Related Articles

  • Comparison of regimens of treatment with sodium stibogluconate in kala-azar. Thakur, C.P.; Kumar, Mahendra; Singh, Satis Kumar; Sharma, Dilip; Prasad, Uma Shanker; Singh, Rama Shray Prasad; Dhawan, P.S.; Achari, Vijay // British Medical Journal (Clinical Research Edition);3/24/1984, Vol. 288 Issue 6421, p895 

    Investigates the regimen of treatment for kala-azar with sodium stibogluconate in Bihar, India. Treatment of 126 kala-azar infected patients; Similarity of symptomatic outcomes; Diagnosis of minor side effects.

  • Comparison of generic and proprietary sodium stibogluconate for the treatment of visceral... Moore, Elinore; O'Flaherty, Deidre; Heuvelmans, Hans; Seaman, Jill; Veeken, Hans; de Wit, Sjoukje; Davidson, Robert N. // Bulletin of the World Health Organization;2001, Vol. 79 Issue 5, p388 

    Objective To compare the use of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis (kala-azar). Methods A total of 102 patients with confirmed kala-azar were treated in a mission hospital in West Pokot region, Kenya, with sodium stibogluconate (20...

  • Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial. Musa, Ahmed; Khalil, Eltahir; Hailu, Asrat; Olobo, Joseph; Balasegaram, Manica; Omollo, Raymond; Edwards, Tansy; Rashid, Juma; Mbui, Jane; Musa, Brima; Abuzaid, Abuzaid Abdalla; Ahmed, Osama; Fadlalla, Ahmed; El-Hassan, Ahmed; Mueller, Marius; Njoroge, Simon; Mucee, Geoffrey; Manduku, Veronica; Mutuma, Geoffrey; Apadet, Lilian // PLoS Neglected Tropical Diseases;Jun2012, Vol. 6 Issue 6, p1 

    Background: Alternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India. Methods: A multi-centre randomized-controlled trial (RCT) to compare efficacy and safety of PM (20 mg/kg/day for...

  • Major Four-year Project Launched to Treat Kala-Azar.  // India -- West;1/27/2012, Vol. 37 Issue 10, pA30 

    The article reports on the kala-azar, a comprehensive four-year project, launched by an international consortium for diagnosis and treatment of visceral leishmaniasis in India and Bangladesh.

  • Evidence that the High Incidence of Treatment Failures in Indian Kala-Azar Is Due to the Emergence of Antimony-Resistant Strains of Leishmania donovani. Lira, Rosalia; Sundar, Shyam; Makharia, A.; Kenney, Richard; Gam, Albert; Saraiva, Elvira; Sacks, David // Journal of Infectious Diseases;8/1/99, Vol. 180 Issue 2 

    Investigates the treatment failures in Kala-Azar infection due to antimony-resistant strains of Leishmania donovani in India. Characterization of kala-azar; Use of splenic aspirates as a source material for the culture of promastigote; Susceptibility of intracellular amastigotes to sodium...

  • Correction: Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India. Ramesh, V.; Singh, Ruchi; Avishek, Kumar; Verma, Aditya; Deep, Deepak Kumar; Verma, Sandeep; Salotra, Poonam // PLoS Neglected Tropical Diseases;12/7/2015, Vol. 9 Issue 12, p1 

    A correction to the article "Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India," by V. Ramesh and colleagues is presented.

  • Gold treatment for kala-azar. Singh, M.P.; Mishra, M.; Khan, A.B.; Ramdas, S.L.; Panjiyar, S. // BMJ: British Medical Journal (International Edition);11/25/89, Vol. 299 Issue 6711, p1318 

    Investigates the use of gold treatment for patients with kala-azar. Enlargement of the liver; Occurrence of leishmania; Toxicity of the gold treatment.

  • Shave Excision as an Adjunct to the Therapy of a Rhinophyma-like Complication in Post-kala-azar Dermal Leishmaniasis. Ramesh, V.; Misra, R.S; Khunger, Niti; Beena, K.R; Salotra, Poonam; Mukherjee, A. // Acta Dermato-Venereologica;6/23/99, Vol. 79 Issue 4, p330 

    Examines the mode on the treatment of rhinophyma-like complication for post-kala-azar dermal leishmaniasis in India. Presence of transient erythema on the nose and cheeks; Prominence of facial erythematous indurations; Effectivity of sodium antimony gluconate.

  • Treatment of Mediterranean visceral leishmaniasis. Gradoni, L.; Bryceson, A. // Bulletin of the World Health Organization;1995, Vol. 73 Issue 2, p191 

    Examines therapeutic approaches for zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries. Drug regiments adopted in the management of ZVL patients in each country; Greece; Morocco; Italy; Malta; Portugal; Spain; Tunisia; Algeria; France.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics