Debendox and congenital malformations in Northern Ireland
- Use of metronidazole and incidence of birth defects. // American Family Physician;1/1/1994, Vol. 49 Issue 1, p205
Focuses on the use of metronidazole and incidence of birth defects as studied by Piper and colleagues and reported in the September 1993 issue of `Obstetrics and Gynecology.' Concerns about teratogenicity; Lack of evidence to indicate birth defects as attributable to metronidazole.
- Effects of acyclovir on pregnancy outcome. // American Family Physician;1/1/1994, Vol. 49 Issue 1, p256
Summarizes a report on the effects of acyclovir on pregnancy outcome which appeared in the October 22, 1993 issue of the `Morbidity and Mortality Weekly Report.' Lack of indication of effects on newborn infants; Diseases treated by acyclovir.
- Phenytoin. // Reactions Weekly;10/19/2013, Issue 1474, p36
The article presents a case study of an 8-year-old girl who developed anonychia after phenytoin exposure in utero.
- ACNE CONTROL VS. BIRTH DEFECTS: Accutane spurs lawsuits, called thalidomide of the '80s. Blodgett, Nancy // ABA Journal;Jul88, Vol. 74 Issue 7, p17
Investigates claims that Accutane, a drug for acute acne, causes severe birth defects in the United States. Accusation that drug maker Roche Laboratories failed to provide warning of the drug's dangers; Recommendation to restrict drug distribution to young women; Allegation that the drug was...
- BeMORE: A Novel Method for Detection of Adverse Fetal Effects Induced by Drugs. Matok, Ilan; Levy, Amalia; Gorodischer, Rafael; Lunenfeld, Eitan; Limony, Yehuda; Koren, Gideon // Current Drug Safety;Feb2011, Vol. 6 Issue 1, p40
We describe a unique new collaboration which allows linkage of administrative databases in Southern Israel, and hence ascertain risk/safety of prescription drugs in pregnancy. The advantages of this system include availibilty of rigorous data confounders, solid data on maternal conditions for...
- New paroxetine pregnancy alert. Cressey, Daniel // Pulse;10/8/2005, Vol. 65 Issue 39, p7
Reports that GlaxoSmithKline PLC has issued a worldwide warning on the use of paroxetine after new research linked the drug to birth defects. Increase the risk of congenital malformation when used during the first trimester; Encouragement of physicians to exercise caution in using the drug in...
- How Safe is Acetaminophen and Pregnancy? Hobbins, John C. // OB/GYN Clinical Alert;Jun2008, Vol. 25 Issue 2, p14
A study evaluates whether acetaminophen, one of the most frequently used drugs among pregnant women, is associated with an increased prevalence of congenital abnormalities.
- Mycophenolate mofetil. // Reactions Weekly;9/15/2007, Issue 1169, p21
The article describes the case of multiple malformations found in a fetus who had been exposed in utero to mycophenolate mofetil (MMF). The 21-year-old mother had lupus nephritis and was receiving maintenance therapy with MMF 1,000 mg twice daily. She was discovered to be pregnant at 25 weeks'...
- Thiamazole. // Reactions Weekly;9/15/2007, Issue 1169, p26
The article describes the case of a 5-year-old girl who developed aplasia cutis congenita following in utero exposure to thiamazole. The girl's mother received thiamazole 20 mg daily for Graves' disease from the time of conception to about four weeks gestation. The girl presented with hairless...