Debendox and congenital malformations in Northern Ireland

Harron, D.W.G.; Griffiths, K.; Shanks, R.G.
November 1980
British Medical Journal;11/22/1980, Vol. 281 Issue 6252, p1379
Academic Journal
Investigates the association of Debendox with congenital abnormalities in Northern Ireland. Environmental factors contributing to a decrease in congenital abnormalities; Influence of drugs on the incidence of fetal abnormalities; Reduction in the incidence of congenital malformations.

Tags: DRUGS -- Side effects;  HUMAN abnormalities


Related Articles

  • Phenytoin.  // Reactions Weekly;10/19/2013, Issue 1474, p36 

    The article presents a case study of an 8-year-old girl who developed anonychia after phenytoin exposure in utero.

  • ACNE CONTROL VS. BIRTH DEFECTS: Accutane spurs lawsuits, called thalidomide of the '80s. Blodgett, Nancy // ABA Journal;Jul88, Vol. 74 Issue 7, p17 

    Investigates claims that Accutane, a drug for acute acne, causes severe birth defects in the United States. Accusation that drug maker Roche Laboratories failed to provide warning of the drug's dangers; Recommendation to restrict drug distribution to young women; Allegation that the drug was...

  • BeMORE: A Novel Method for Detection of Adverse Fetal Effects Induced by Drugs. Matok, Ilan; Levy, Amalia; Gorodischer, Rafael; Lunenfeld, Eitan; Limony, Yehuda; Koren, Gideon // Current Drug Safety;Feb2011, Vol. 6 Issue 1, p40 

    We describe a unique new collaboration which allows linkage of administrative databases in Southern Israel, and hence ascertain risk/safety of prescription drugs in pregnancy. The advantages of this system include availibilty of rigorous data confounders, solid data on maternal conditions for...

  • New paroxetine pregnancy alert. Cressey, Daniel // Pulse;10/8/2005, Vol. 65 Issue 39, p7 

    Reports that GlaxoSmithKline PLC has issued a worldwide warning on the use of paroxetine after new research linked the drug to birth defects. Increase the risk of congenital malformation when used during the first trimester; Encouragement of physicians to exercise caution in using the drug in...

  • Methotrexate/misoprostol.  // Reactions Weekly;1/13/2007, Issue 1134, p18 

    The article presents several case reports on drug-induced congenital disorders in infants. It references a study by N. T. Yedlinsky and colleagues published in the May 2005 issue of "Obstetrics and Gynecology." Two women received oral methotrexate and intravaginal misoprostol during 6-7 weeks of...

  • Safety of lopinavir/ritonavir use in pregnancy investigated.  // Reactions Weekly;8/22/2009, Issue 1266, p5 

    The article discusses research on the use of lopinavir/ritonavir in pregnancy. It references a study by S. S. Roberts and colleagues, published in the August 2009 issue of the "Journal of Acquired Immune Deficiency Syndrome." Researchers found that lopinavir and ritonavir do not seem to increase...

  • Paroxetine (Paxil) and congenital malformations. Williams, Megan; Wooltorton, Eric // CMAJ: Canadian Medical Association Journal;11/22/2005, Vol. 173 Issue 11, p1320 

    Focuses on a study on the association of paroxetine with congenital malformations conducted by GlaxoSmithKline. Common disorders during the childbearing years treated with antidepressants; Physiological effects of bupropion and paroxetine; Absolute rate of major congenital seen in the first...

  • Adverse Drug Reactions In Utero: Perspectives on Teratogens and Strategies for the Future. Mitchell, A. A. // Clinical Pharmacology & Therapeutics;Jun2011, Vol. 89 Issue 6, p781 

    Many think of an adverse drug reaction (ADR) as an adverse event caused by a medication intended for a given subject. However, as we learned from the thalidomide debacle 50 years ago, some of the most devastating ADRs affect not the subject who takes the medication but rather, in the case of...

  • How Safe is Acetaminophen and Pregnancy? Hobbins, John C. // OB/GYN Clinical Alert;Jun2008, Vol. 25 Issue 2, p14 

    A study evaluates whether acetaminophen, one of the most frequently used drugs among pregnant women, is associated with an increased prevalence of congenital abnormalities.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics