TITLE

THINKING OUTSIDE THE BLACK BOX: THE RELATIVE RISK OF SUICIDALITY IN ANTIDEPRESSANT USE

AUTHOR(S)
Goldstein, Elizabeth A.; Ruscio, John
PUB. DATE
May 2009
SOURCE
Scientific Review of Mental Health Practice;2009, Vol. 7 Issue 1, p3
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The Food and Drug Administration issued a black box warning in response to concerns that antidepressants may increase the risk or suicidality in children and young adults. In the effort to weigh the benefits and risks of anti-depressants, numerous methodological challenges preclude the determination of a definitive answer. The available empirical findings and mixed, with some studies displaying an association between antidepressant use and reduced suicidality, and other studies uncovering a significant risk of suicidality for patients treated with antidepressants compared to placebo. In the absence of more conclusive information regarding the relative safety and efficacy of antidepressant medication, frequent monitoring, especially during the first weeks of treatment, should be a component of all treatment plans. Further research is needed to determine which patients might benefit most from antidepressant treatment, as well as whether the black box warning has prevented suicide, or merely hindered the prescription of potentially helpful medication.
ACCESSION #
49050664

 

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