O efeito da obesidade sobre parâmetros espirométricos em adolescentes submetidos à broncoprovocação por exercício

Cieslak, Fabrício; Milano, Gerusa Eisfeld; Lopes, Wendell Artur; Radominski, Rosana Bento; Leite, Nelson Augusto Rosário Filho e Neiva
January 2010
Acta Scientiarum: Health Sciences;Jan-Jun2010, Vol. 32 Issue 1, p43
Academic Journal
The objective of this study was to evaluate the effect of obesity on spirometric parameters in adolescents subjected to a physical exercise bronchoprovocation test. It was a cross-sectional, descriptive and correlational study composed of 15 adolescents of both genders. The diagnosis of asthma was made by clinical history and ISAAC questionnaire, and obesity by BMI above the 95th percentile. The bronchoprovocation test with physical exercise was used for assessment of exercise induced asthma (EIA), considering positive a decrease in forced expiratory volume in one second (FEV1) > 10% of pre-exercise, and the intensity was calculated by the EIA maximum percentage fall in FEV1 (% Fallmax FEV1). We used the independent t test or Mann-Whitney U test and the Spearman rho correlation (p < 0.05). Significant differences were found between asthmatics and non-asthmatics to % Fallmax FEV1 (p = 0.034). There was a negative moderate relationship to Fallmax FEV1 with leukocytes, and % Fallmax FEV1 with leukocytes. It can be concluded that the spirometric variables presented moderated correlation with the systemic inflammation of obesity.


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