TITLE

Tuberculosis of the Elbow Joint in Children

AUTHOR(S)
Agarwal, Anil; Mumtaz, Imran; Kumar, Pawan; Shariq Khan; Qureshi, Nadeem Aktar
PUB. DATE
February 2010
SOURCE
Journal of Bone & Joint Surgery, American Volume;Feb2010, Vol. 92-A Issue 2, p436
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: There is scarce information regarding osteoarticular tuberculosis of the elbow in children, even in countries where tuberculosis is endemic. We report our experience with ten patients who were managed nonoperatively. Methods: We retrospectively assessed ten children with elbow tuberculosis with regard to their presentation, diagnosis, management, response to standard antitubercular drugs, and outcome at the completion of antitubercular therapy. All patients were managed nonoperatively with splinting for as long as six weeks, followed by mobilization along with multidrug antitubercular medication for twelve months. Results: Swelling of the elbow that did not respond to initial treatment was the most common cause for referral to our clinic. The proximal ulnar metaphysis was most commonly involved. The average duration of follow-up was twenty-six months. The average time for healing of draining sinuses was twelve weeks (range, four to fourteen weeks). Lytic lesions, including coke-like sequestrum, healed radiographically at an average of 7.4 months (range, six to nine months). Range of motion improved with treatment, but some motion restriction always persisted, depending on the extent of joint destruction. Conclusions: In the Indian subcontinent, the presentation of elbow tuberculosis is usually exudative with abscess formation, and the disease is fairly advanced at the time of diagnosis. An "ice cream scoop" appearance of the proximal part of the ulna in children should raise suspicion for tuberculosis. Elbow tuberculosis in children can be treated adequately with use of nonoperative means, regardless of the extent of osseous destruction, with a good outcome.
ACCESSION #
48983917

 

Related Articles

  • Synthesis and Antituberculosis Activity of Cycloalkylidenehydrazide and 4-Aza-1- thiaspiro[4.5]decan-3-one Derivatives of Imidazo[2,1-b]thiazole. Ulusoy, Nuray // Drug Research / Arzneimittel-Forschung (Editio Cantor Verlag fur;Jul2002, Vol. 52 Issue 7, p565 

    New N&sup 2;-cycloalkylidene- (6-phenyl/4-chlorophenylimidazo [2,l-b] thiazol-3-yl) acetic acid hydrazides (2a-h and 3a-b) were synthesized by reacting (6-phenyl/ 4-chlorophenylimidazo [2,1-b] thiazol- 3-yl) acetic acid hydrazides with cyclohexanones or cyclopentanone. Furthermore, 2a-h were...

  • Chemotherapy of Pulmonary Tuberculosis. Johnston, Robert F.; Hopewell, Philip C. // Annals of Internal Medicine;Feb69, Vol. 70 Issue 2, p359 

    Examines some of the concepts in the chemotherapy of pulmonary tuberculosis. Treatment of the newly diagnosed case; Advantages of short-term hospitalization of persons either having or suspected of having pulmonary tuberculosis; Drug regimens; Chemotherapy of the primary treatment failure.

  • Pharmacovigilance and tuberculosis: applying the lessons of thioacetazone. Falzon, Dennis; Hill, Geraldine; Pal, Shanthi N.; Suwankesawong, Wimon; Jaramillo, Ernesto // Bulletin of the World Health Organization;Dec2014, Vol. 92 Issue 12, p918 

    In this article the authors discuss pharmacovigilance and its relationship to tuberculosis. They are supportive of monitoring the production and utilization of newly developed tuberculosis drugs which are designed to fight against drug-resistant tuberculosis to ensure public safety and avoid...

  • Effective identification, treatment and prevention is key in the war on tuberculosis.  // Drugs & Therapy Perspectives;Nov2006, Vol. 22 Issue 11, p8 

    The incidence of tuberculosis is increasing, especially in developing countries. Antitubercular regimens include different combinations of first-line drugs that quickly kill multiplying bacilli, reducing resistance and preventing spread, followed by a longer course to eradicate semidormant...

  • Delamanid for multidrug-resistant pulmonary tuberculosis.  // African Journal of Respiratory Medicine;Sep2012, Vol. 8 Issue 1, p2 

    The article reports on the multicentre trial reported in the "New England Journal of Medicine" which shows the effectiveness of the antituberculous drug delamanid for treatment of multidrug-resistant pulmonary tuberculosis.

  • Isoniazid-Resistant Tuberculous Meningitis, United States, 1993-2005. Vinnard, Christopher; Winston, Carla A.; Wileyto, E. Paul; MacGregor, Rob Roy; Bisson, Gregory P. // Emerging Infectious Diseases;Mar2011, Vol. 17 Issue 3, p539 

    To determine patient characteristics associated with isoniazid resistance in cases of tuberculous meningitis, we conducted a cross-sectional study by using data from the US National Tuberculosis Surveillance System during 1993-2005. Foreign-born patients were more likely to be infected with an...

  • SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF SOME SUBSTITUTED 2, 3-SUBSTITUTED QUINAZOLINONE ANALOGS. Rajasekaran, S.; Rao, Gopalkrishna; Niranjan, H. S. // International Journal of Pharmaceutical Sciences & Research;Nov2012, Vol. 3 Issue 11, p4394 

    In recent years, there is a tremendous increase of drug resistant pathogens, leading to the design and development of newer antitubercular agents. A series of 2-(substituted-phenyl)-1,3-benzoxazin-4-ones and 3-amino-2-(substituted-phenyl)quinazolin-4(3H)-ones were synthesized by the reaction of...

  • Prediction of physiochemical parameters for anti-tubercular potentials of Mannich and Schiff bases. K., Umaa.; S., Sudha Rani.; G., Sangeetha.; E., Maida Engels. S. // Journal of Chemical & Pharmaceutical Research;2013, Vol. 5 Issue 4, p52 

    A quantitative structure activity relationship study was performed on series of substituted Mannich bases of 5-hydroxy-2-methyl-4H-pyran-4-ones and Schiff's bases of Benzothiazole obtained from an elaborate literature survey as anti-tuberculosis compounds for establishing quantitative...

  • Melioidosis: Another "Great Mimic".  // Clinical Infectious Diseases;1/15/2009, Vol. 48 Issue 2, piv 

    The article provides information on a research about melioidosis. The study presented 22 patients with melioidosis who were febrile, despite having received antituberculous therapy. Based on the results, the researchers concluded that melioidosis has the ability to mimic other infectious...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics