Benefits and risks associated with β-blocker prophylaxis in noncardiac surgery

White, C. Michael; Talati, Ripple; Phung, Olivia J.; Baker, William L.; Reinhart, Kurt; Sedrakyan, Art; Kluger, Jeffrey; Coleman, Craig I.
April 2010
American Journal of Health-System Pharmacy;4/1/2010, Vol. 67 Issue 7, p523
Academic Journal
The article focuses on the benefits and risks factors associated with the use of B-blocker prophylaxis in noncardiac surgeries (NCSs). It discusses the clinical trials which evaluated the effect of perioperative B-blockers on myocardial infarction (MI), stroke, and hypotension. It says that perioperative use of B-blockers in NCS can protect patients against postoperative MI, but increases the risk of stroke, severe hypotension, and severe bradycardia.


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