Spectral tagging by integrated photonic crystal resonators for highly sensitive and parallel detection in biochips

Martiradonna, Luigi; Pisanello, Ferruccio; Stomeo, Tiziana; Qualtieri, Antonio; Vecchio, Giuseppe; Sabella, Stefania; Cingolani, Roberto; De Vittorio, Massimo; Pompa, Pier Paolo
March 2010
Applied Physics Letters;3/15/2010, Vol. 96 Issue 11, p113702
Academic Journal
We propose a technological approach aimed at improving biochips performances, based on an efficient spectral modeling and enhancement of markers fluorescence through the insertion of photonic crystal nanocavities (PhC-NCs) in the readout area of biochips. This strategy univocally associates a specific emission wavelength to a specific bioprobe immobilized on a nanocavity, therefore guaranteeing parallel detection of multiple elements and faster analysis time. Moreover, PhC-NCs significantly enhance the markers fluorescence, thus improving the detection sensitivity.


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