The fetal and infant origins of adult disease: The womb may be more important than the home

Barker, D.J.P.
November 1990
BMJ: British Medical Journal (International Edition);11/17/90, Vol. 301 Issue 6761, p1111
Academic Journal
Examines processes linking fetal and infant growth with cardiovascular disease. Risk of hypertension; Discordance between placental and birth weights; Effect of infant food in motor development of preterm babies.


Related Articles

  • Early and Late Postnatal Myocardial and Vascular Changes in a Protein Restriction Rat Model of Intrauterine Growth Restriction. Menendez-Castro, Carlos; Fahlbusch, Fabian; Cordasic, Nada; Amann, Kerstin; Münzel, Kathrin; Plank, Christian; Wachtveitl, Rainer; Rascher, Wolfgang; Hilgers, Karl F.; Hartne, Andrea // PLoS ONE;2011, Vol. 6 Issue 5, p1 

    Intrauterine growth restriction (IUGR) is a risk factor for cardiovascular disease in later life. Early structural and functional changes in the cardiovascular system after IUGR may contribute to its pathogenesis. We tested the hypothesis that IUGR leads to primary myocardial and vascular...

  • Fetal and placental size and risk of hypertension in adult life. Barker, D.J.P.; Bull, A.R.; Osmond, C.; Simmonds, S.J. // BMJ: British Medical Journal (International Edition);8/4/90, Vol. 301 Issue 6746, p259 

    Examines the effect of intrauterine growth and maternal physique on blood pressure in adult life in Great Britain. Effect of the discordance between placental and fetal size on the circulatory adaptation of the fetus; Recommendation of improving the nutrition and health of mothers; Link between...

  • Hypertension epidemiology in India: lessons from Jaipur Heart Watch. Gupta, Rajeev; Gupta, V. P. // Current Science (00113891);8/10/2009, Vol. 97 Issue 3, p349 

    Cardiovascular diseases have emerged as an important health problem in India. High blood pressure (BP) is a major risk factor and better control can lead to prevention of 300,000 of the 1.5 million annual deaths from cardiovascular diseases in India. Epidemiological studies demonstrate that...

  • THE PREVALENCE OF THE METABOLIC SYNDROME AND CARDIOVASCULAR DISEASE RISK USING THREE PROPOSED DEFINITIONS. Szurkowsko, M.; Szafroniec, K.; Gilis-Januszewska, A. // Journal of Epidemiology & Community Health;Aug2004 Supplement 1, Vol. 58, pA55 

    The article focuses on the study related to prevalence of the metabolic syndrome and cardiovascular disease. The metabolic syndrome (MetS), a concurrence of disturbed glucose and insulin metabolism, overweight, and abdominal fat distribution, dyslipidoemia and hypertension, is associated with...

  • The Ideal Cardiovascular Health Metrics Associated Inversely with Mortality from All Causes and from Cardiovascular Diseases among Adults in a Northern Chinese Industrial City. Liu, Yan; Chi, Hong-jie; Cui, Liu-fu; Yang, Xin-chun; Wu, Yun-tao; Huang, Zhe; Zhao, Hai-yan; Gao, Jing-sheng; Wu, Shou-ling; Cai, Jun // PLoS ONE;Feb2014, Vol. 9 Issue 2, p1 

    Background and Aims: The American Heart Association has recently established seven ideal cardiovascular health metrics for cardiovascular health promotion and disease reduction (i.e., non-smoking, normal body mass index, physically active, healthy diet, and normal levels of cholesterol, blood...

  • Hypertension: Prevalence and its Associated Factors in a Rural South Indian Population. Madhu, B.; Srinath, K. M.; Ashok, N. C. // Indian Journal of Public Health Research & Development;Oct-Dec2012, Vol. 3 Issue 4, p105 

    Background: Cardiovascular diseases are the leading causes of morbidity and mortality in the world. It has been predicted that most of the increase in the cardiovascular diseases will be occurring in the developing countries. Hypertension is not only the main factor involved in the pathogenesis...

  • Angiotensin II type 1 receptor polymorphisms in the cardiovascular health study: relation to blood pressure, ethnicity, and cardiovascular events. Hindorff, Lucia A.; Heckbert, Susan R.; Tracy, Russell; Tang, Zhonghua; Psaty, Bruce M.; Edwards, Karen L.; Siscovick, David S.; Kronmal, Richard A.; Nazar-Stewart, Valle // American Journal of Hypertension;Dec2002, Vol. 15 Issue 12, p1050 

    : BackgroundThe angiotensin II type 1 receptor A1166C polymorphism has been associated with increased risks of hypertension and myocardial infarction in several small studies. We examined the association between this polymorphism and new-onset hypertension, blood pressure (BP) control, and...

  • Prevalence of hypertension and its associated factors in contaminated areas of the Santos-São Vicente Estuarine region and Bertioga, Brazil: 2006-2009. Ribeiro, T.; Carvalho, D.; Guimarães, M.; Campina, N.; Lobarinhas, M.; Lopes, A.; Cunha, M.; Souza, I.; Oliveira, V.; Martins, L.; Gomes, A.; Pereira, L.; Braga, A. // Environmental Science & Pollution Research;Oct2016, Vol. 23 Issue 19, p19387 

    In Brazil, cardiovascular diseases account for 33% of deaths and the prevalence of hypertension is of approximately 22%. The Santos and São Vicente Estuarine System is the most important example of environmental degradation by chemicals from industrial sources. The aim of the present study...

  • The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life. Barker, D.J.P.; Osmond, C.; Simmonds, S.J.; Wield, G.A. // BMJ: British Medical Journal (International Edition);2/13/93, Vol. 306 Issue 6875, p422 

    Examines the relations of fetal growth to death from cardiovascular disease in adult life. Decrease in the mortality ratios for cardiovascular disease; Link between fetal growth and duration of gestation; Genesis of the reduction in fetal growth.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics