Four probe architecture using high spatial resolution single multi-walled carbon nanotube electrodes for electrophysiology and bioimpedance monitoring of whole tissue

de Asis Jr., Edward D.; Leung, Joseph; Wood, Sally; Nguyen, Cattien V.
March 2010
Applied Physics Letters;3/1/2010, Vol. 96 Issue 9, p093701
Academic Journal
We report the application of a sensor with a multielectrode architecture consisting of four single multiwalled carbon nanotube electrodes (sMWNT electrodes) with nanotube tip diameters of approximately 30 nm to stimulation, recording, and bioimpedance characterization of whole muscle. Parallel pairs of sMWNT electrodes achieve improved stimulation efficiency from a reduction in electrode impedance and enhanced signal-to-noise ratio by detecting endogenic signals from a larger population of electrically active cells. The sensor with a four sMWNT electrode configuration can monitor changes in whole tissue bioimpedance.


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