Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids: novel imaging findings

Boiss´, Lysa; Islam, Omar; Woulfe, John; Ludwin, Samuel K.; Brunet, Donald G.
March 2010
Journal of Neurology, Neurosurgery & Psychiatry;Mar2010, Vol. 81 Issue 3, p313
Academic Journal
The article offers information on the imaging and clinical findings of adult onset of hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS). It presents the case of a 46-year-old man diagnosed with the disease in which magnetic resonance imaging revealed (MRI) bilateral increased T2 signal intensity within the frontoparietal white matter. Moreover, imaging characterisation of the disease may decrease the requirement for brain biopsy.


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