TITLE

Pathology of Gastric Intestinal Metaplasia: Clinical Implications

AUTHOR(S)
Correa, Pelayo; Piazuelo, M. Blanca; Wilson, Keith T.
PUB. DATE
March 2010
SOURCE
American Journal of Gastroenterology;Mar2010, Vol. 105 Issue 3, p493
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the pathology of gastric intestinal metaplasia (IM). It enables clinicians to identify subgroups of patients with IM at increased risk for gastric cancer and propose an algorithm for the management of gastric IM. It explores various diagnostic methods such as topographic mapping and pepsinogen assessment. It cites that a histopathologic diagnosis of complete type of IM is not an indication for prolonged surveillance unless other gastric cancer risk indicators are present.
ACCESSION #
48400305

 

Related Articles

  • Serum Pepsinogen I as a Predictor of Stomach Cancer. Nomura, Abraham M. Y.; Stemmermann, Grant N.; Samloff, I. Michael // Annals of Internal Medicine;Oct80, Vol. 93 Issue 4, p537 

    Presents a study which investigated the hypothesis that a low serum pepsinogen I level might also be subclinical marker of increased susceptibility for gastric cancer. Correlationn between intestinal metaplasia and intestinal-mixed-other types of gastric cancer; Methods used; Discussion,

  • Atrophic gastritis in young children and adolescents. Ricuarte, O.; Gutierrez, O.; Cardona, H.; Kim, J. G.; Graham, D. Y.; El-Zimaity, H. M. T. // Journal of Clinical Pathology;Nov2005, Vol. 58 Issue 11, p1189 

    Background: Helicobacter pylori associated gastric cancer arises via a multistage process, with atrophic gastritis being the precursor lesion. Helicobacter pylori is typically acquired in childhood, yet little is known of the prevalence of atrophic gastritis in childhood. Aim: To study atrophic...

  • Usefulness of gastric cancer screening using the serum pepsinogen test method. Miki, Kazumasa; Morita, Masuo; Sasajima, Masahiko; Hoshina, Reiko; Kanda, Eiko; Urita, Yoshihisa // American Journal of Gastroenterology;Apr2003, Vol. 98 Issue 4, p735 

    : ObjectiveThe measurement of serum pepsinogen has recently gained attention as a candidate for a new screening test for gastric cancer. This method is particularly attractive given its lower cost and simplicity to administer relative to photofluorography. To compare the accuracy between the two...

  • Advanced Gastric Carcinoma With a Complete Intestinal Metaplasia Phenotype Associated With Early Intestinal-Type Carcinoma. Rivera-Hueto, Francisco; Lag-Asturiano, Encarnación; Utrilla-Alcolea, José C.; Herrerías-Gutiérrez, Juan M. // Archives of Pathology & Laboratory Medicine;Feb2004, Vol. 128 Issue 2, p218 

    Presents a case study of advanced gastric carcinoma with a complete intestinal metaplasia phenotype associated with early intestinal-type carcinoma. Stains positive in the advanced adenocarcinoma; Characteristics of the cancer; Lesions included in the gastrectomy specimen.

  • Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer. Dongmei Li; Jun Zhang; Yu Xi; Lei Zhang; Wenmei Li; Jiantao Cui; Rui Xing; Yuanmin Pan; Zemin Pan; Feng Li; Youyong Lu // BMC Cancer;12/1/2015, Vol. 15, p1 

    Background: Our previous proteomic analysis revealed that mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein (MAWBP) were downregulated in gastric cancer (GC) tissues. These proteins interacted and formed complexes in GC cells. To investigate the role of...

  • The new modified ABCD method for gastric neoplasm screening. Park, Chan; Kim, Eun; Jung, Da; Chung, Hyunsoo; Park, Jun; Shin, Sung; Lee, Sang; Lee, Yong // Gastric Cancer;Jan2016, Vol. 19 Issue 1, p128 

    Background: The ABCD screening method was developed for risk stratification of gastric cancer. It is unclear whether the ABCD method can predict the risk of gastric neoplasms, including gastric adenomas, as observed for gastric cancer. We aimed to devise a modified ABCD method for predicting...

  • Validity of Serum Pepsinogen I/II Ratio for the Diagnosis of Gastric Epithelial Dysplasia and Intestinal Metaplasia during the Follow-Up of Patients at Risk for Intestinal-Type Gastric Adenocarcinoma. Dinis-Ribeiro, Mário; Da Costa-Pereira, Altamiro; Lopes, Carlos; Barbosa, Joana; Guilherme, Mateus; Moreira-Dias, Luís; Lomba-Viana, Helena; Silva, Rui; Abreu, Nuno; Lomba-Viana, Rafael // Neoplasia;Sep/Oct2004, Vol. 6 Issue 5, p449 

    A cohort of individuals (n = 136) with lesions as severe as atrophic chronic gastritis (ACG) was cross-sectionally evaluated for the validity assessment of pepsinogen I (PGI) and pepsinogen II (PGII) serum levels for the diagnosis of intestinal metaplasia (IM) and gastric dysplasia. PGI/PGII...

  • Malignant Transformation of Benign Epithelial Gastric Polyps. Orlowska, Janina; Jarosz, Dornta; Pachlewski, Jacek; Butruk, Eugeniusz // American Journal of Gastroenterology;Dec1995, Vol. 90 Issue 12, p2152 

    Objectives: To compare the malignant potential of hyperplastic polyps and adenomas in relation to different histological classifications and to try to follow the natural history, of the BEGP-carcinoma sequence. Methods: During a 13-yr period (1981-1993), 811 BEGP were discovered in 432 patients...

  • The Detection of Premalignant and Malignant Gastric Lesions by Conventional Endoscopy in a General Population Sample. Alina, Boeriu; Daniela, Dobru; Ofelia, Pascarenco; Simona, Mocan // Acta Medica Marisiensis;Apr2011, Vol. 57 Issue 2, p136 

    Background and Aims: The identification of patients with premalignant lesions and endoscopic surveillance could improve the early detection of gastric cancer, with better therapy and prognosis. We performed conventional endoscopy with biopsies to identify the incidence rates of premalignant and...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics