Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus

December 2009
International Journal of Advances in Rheumatology;2009, Vol. 7 Issue 4, p122
Academic Journal
High-density lipoproteins (HDL) are not always "the good cholesterol". In the setting of inflammation, HDL may become pro-atherogenic. In this study, the authors confirm that pro-inflammatory HDL (piHDL) is common in systemic lupus erythematosus and find that it represents a powerful independent risk factor for subclinical atherosclerosis.


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