Insulin Sensitivity in Prepubertal Caucasian Normal Weight Children

Masuccio, Fabio G.; Lattanzio, Franca M.; Matera, Sabino; Giannini, Cosimo; Chiarelli, Francesco; Mohn, Angelika
August 2009
Journal of Pediatric Endocrinology & Metabolism;Aug2009, Vol. 22 Issue 8, p695
Academic Journal
The article examines the reliability of reference values provided by the homeostasis model assessment of insulin resistance (HOMA-IR) and the whole body insulin sensitivity index (WBISI) in determining whether or not a prepubertal Caucasian child is insulin-resistant. It compares the two tests with other tests such as the frequent sampling intravenous glucose tolerance test (FS-IVGTT) and the euglycemic insulin clamp. It elaborates percentile patterns for HOMA-IR and WBISI that are relevant to prepubertal Caucasian children with normal weights.


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